SCHEMBL6787299

SCHEMBL6787299

Cc1ccc(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc(C)cc3)CC(N(C)C)C2)cc1

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.62
MEN1 O00255 4/20 0.62
HTT P42858 2/20 0.62
PKM P14618 3/20 0.62
ALDH1A1 P00352 3/20 0.60
POLB P06746 1/20 0.60
GAA P10253 3/20 0.56
TSHR P16473 1/20 0.55
CYP2C19 P33261 1/20 0.55
LMNA P02545 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19092139 0.84 KMT2A (0.62) KMT2AMEN1HTTPKMALDH1A1
SCHEMBL3971438 0.80 PKM (0.88) KMT2AMEN1HTTPKMALDH1A1
SCHEMBL3303527 0.80 PKM (0.88) KMT2AMEN1HTTPKMALDH1A1
SCHEMBL8200466 0.80 PKM (0.88) KMT2AMEN1HTTPKMALDH1A1
SCHEMBL565301 0.80 PKM (0.88) KMT2AMEN1HTTPKMALDH1A1
SCHEMBL699639 0.80 PKM (0.88) KMT2AMEN1HTTPKMALDH1A1
SCHEMBL10724066 0.80 PKM (0.88) KMT2AMEN1HTTPKMALDH1A1
SCHEMBL8203532 0.80 PKM (0.88) KMT2AMEN1HTTPKMALDH1A1
SCHEMBL4537086 0.80 PKM (0.88) KMT2AMEN1HTTPKMALDH1A1
SCHEMBL14251942 0.80 PKM (0.66) KMT2AMEN1HTTPKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6828316-B2 Antiallergens KOWA CO., LTD. (JP) 2004-12-07 US disclosed
US-20020042414-A1 Diamide compound and medicine containing the same KOWA CO., LTD. (JP) 2002-04-11 US disclosed
US-6340682-B1 FOR THERAPY OF ALLERGIC IMMUNOLOGICAL DISEASE IS SELECTED FROM ASTHMA, ALLERGIC RHINITIS, INFLAMMATORY LARGE BOWEL DISEASE OR CONTACT DERMATITIS KOWA CO., LTD. (JP) 2002-01-22 US disclosed
EP-0926138-A1 DIAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME KOWA CO. LTD. (JP) 1999-06-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020042414-A1 Diamide compound and medicine containing the same HRH4, HRH2, HRH1 KMT2A 439/4885MEN1 3292/4885HTT 2457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.