Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19414179 | 0.84 | MAPT (0.52) | MAPTGAATSHRHTTALOX15 | |
| SCHEMBL2842314 | 0.83 | MAPT (0.48) | MAPTGAATSHRHTTALOX15 | |
| SCHEMBL29143540 | 0.73 | GAA (0.50) | MAPTGAATSHRHTTALOX15 | |
| SCHEMBL9918370 | 0.71 | MC4R (0.64) | MAPTTSHRHTTALDH1A1MC4R | |
| SCHEMBL19274402 | 0.70 | ALOX5 (0.41) | MAPTTSHRALDH1A1HPGD | |
| SCHEMBL8903906 | 0.69 | ATM (0.54) | TSHRHTTATMALDH1A1HPGD | |
| SCHEMBL19830553 | 0.67 | NPC1 (0.44) | TSHRALDH1A1CYP3A4CYP2D6HPGD | |
| SCHEMBL22639910 | 0.67 | TP53 (0.64) | MAPTGAATSHRALOX15ALDH1A1 | |
| SCHEMBL22640018 | 0.67 | TP53 (0.64) | MAPTGAATSHRALOX15ALDH1A1 | |
| SCHEMBL8196150 | 0.66 | L3MBTL1 (0.39) | MAPTGAAHTTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122834-A1 | SMALL MOLECULE CD4 MIMETICS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122834-A1 | SMALL MOLECULE CD4 MIMETICS AND USES THEREOF | CD4, CCR1, RORC | MAPT 4771/4885GAA 4351/4885TSHR 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.