⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL947688 | 0.97 | FDPS (0.36) | — | |
| SCHEMBL28293099 | 0.79 | MC4R (0.38) | — | |
| SCHEMBL7658761 | 0.77 | FDPS (0.40) | — | |
| SCHEMBL947453 | 0.77 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL3132191 | 0.77 | CHRM2 (0.34) | — | |
| SCHEMBL10694399 | 0.74 | GPR119 (0.37) | — | |
| SCHEMBL8135026 | 0.72 | — | — | |
| SCHEMBL66078 | 0.72 | — | — | |
| SCHEMBL5441028 | 0.72 | — | — | |
| SCHEMBL964312 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487806-B1 | 4-ANILINO QUINAZOLINE DERIVATIVES AS ANTIPROLIFERATIVE AGENTS | ASTRAZENECA AB (SE) | 2010-07-07 | — | — | EP | claimed |
| US-4267340-A | BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-12 | — | — | US | claimed |
| US-4009159-A | PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-02-22 | — | — | US | claimed |
| US-3993646-A | Process for the ring expansion of penicillins to cephalosporin compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-11-23 | — | — | US | claimed |
| EP-2160192-B1 | ANTIMICROBIAL MATERIALS AND COATINGS | COVIDIEN LP (US) | 2018-03-28 | — | — | EP | disclosed |
| US-20170096391-A1 | NOVEL LACTAMS | BIOSIGNAL LIMITED (AU) | 2017-04-06 | — | — | US | disclosed |
| US-9586901-B2 | Lactams | UNILEVER PLC (GB) | 2017-03-07 | — | — | US | disclosed |
| US-8586618-B2 | Furanone compounds and lactam analogues thereof | BIOSIGNAL LIMITED (AU) | 2013-11-19 | — | — | US | disclosed |
| EP-2177226-B1 | Hydroxamate compositions | COVIDIEN LP (US) | 2013-09-18 | — | — | EP | disclosed |
| US-20130190377-A1 | Novel Lactams | BIOSIGNAL LIMITED (AU) | 2013-07-25 | — | — | US | disclosed |
| US-8425972-B2 | Antimicrobial materials and coatings | COVIDIEN LP (US) | 2013-04-23 | — | — | US | disclosed |
| US-8399667-B2 | 4-anilino quinazoline derivatives as antiproliferative agents | ASTRAZENECA AB (GB) | 2013-03-19 | — | — | US | disclosed |
| US-4182727-A | 4-[6-(4-Cyanophenoxy)hexyl]-3,5-heptanedione | STERLING DRUG INC. (US) | 1980-01-08 | — | — | US | disclosed |
| US-4171376-A | Aryloxyalkyl keto-esters | STERLING DRUG INC. (US) | 1979-10-16 | — | — | US | disclosed |
| US-4169150-A | MUSCLE RELAXANTS, HYPNOSIS, ANTICONVULSANTS, SEDATIVES | TEIJIN LIMITED (JP) | 1979-09-25 | — | — | US | disclosed |
| US-4138553-A | 3-Methylene cephalosporanic acid derivatives and process for preparation thereof | TEIJIN LIMITED (JP) | 1979-02-06 | — | — | US | disclosed |
| US-4133959-A | Aryloxyalkyl diketones | STERLING DRUG INC. (US) | 1979-01-09 | — | — | US | disclosed |
| US-4036847-A | ANTIBACTERIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-07-19 | — | — | US | disclosed |
| US-4009159-A | PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-02-22 | — | — | US | disclosed |
| US-3993646-A | Process for the ring expansion of penicillins to cephalosporin compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-11-23 | — | — | US | disclosed |