Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16982014 | 0.89 | CYP1A2 (0.42) | TP53LMNASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL19368263 | 0.81 | CYP1A2 (0.62) | LMNAKMT2AMC4RALDH1A1OPRM1 | |
| SCHEMBL16461973 | 0.79 | RPS6KB1 (0.50) | TP53LMNAP2RX7THRBPOLB | |
| SCHEMBL28751840 | 0.79 | TP53 (0.50) | TP53LMNAP2RX7THRBPOLB | |
| SCHEMBL3669763 | 0.77 | RPS6KB1 (0.49) | TP53LMNAP2RX7THRBPOLB | |
| SCHEMBL16461381 | 0.75 | RPS6KB1 (0.50) | TP53LMNAP2RX7THRBSLC6A2 | |
| SCHEMBL4731651 | 0.75 | TP53 (0.47) | TP53LMNAP2RX7THRBPOLB | |
| SCHEMBL22206739 | 0.74 | CHRM2 (0.57) | TP53LMNASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL22206767 | 0.74 | CHRM2 (0.57) | TP53LMNASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8716792 | 0.70 | ADRB2 (0.48) | TP53LMNASLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122834-A1 | SMALL MOLECULE CD4 MIMETICS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122834-A1 | SMALL MOLECULE CD4 MIMETICS AND USES THEREOF | CD4, CCR1, RORC | TP53 1569/4885LMNA 3342/4885P2RX7 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.