Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG2 | P16885 | 1/20 | 0.68 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.67 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.67 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.67 |
| ▸ | F2 | P00734 | 1/20 | 0.65 |
| ▸ | F10 | P00742 | 1/20 | 0.65 |
| ▸ | PLG | P00747 | 1/20 | 0.65 |
| ▸ | PLAU | P00749 | 1/20 | 0.65 |
| ▸ | PLAT | P00750 | 1/20 | 0.65 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.65 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28340004 | 1.00 | PLCG2 (0.68) | PLCG2CSNK2A2CSNK2BCSNK2A1F2 | |
| SCHEMBL6789114 | 1.00 | PLCG2 (0.68) | PLCG2CSNK2A2CSNK2BCSNK2A1F2 | |
| SCHEMBL11974092 | 0.92 | PLCG2 (0.78) | PLCG2CSNK2A2CSNK2BCSNK2A1F2 | |
| SCHEMBL6802454 | 0.89 | CSNK2A2 (0.81) | PLCG2CSNK2A2CSNK2BCSNK2A1F2 | |
| SCHEMBL6802450 | 0.89 | CSNK2A2 (0.81) | PLCG2CSNK2A2CSNK2BCSNK2A1F2 | |
| SCHEMBL4691058 | 0.89 | DAPK3 (0.75) | PLCG2CSNK2A2CSNK2BCSNK2A1F2 | |
| SCHEMBL2131615 | 0.89 | DAPK3 (0.75) | PLCG2CSNK2A2CSNK2BCSNK2A1F2 | |
| SCHEMBL2131623 | 0.89 | DAPK3 (0.75) | PLCG2CSNK2A2CSNK2BCSNK2A1F2 | |
| SCHEMBL24418239 | 0.85 | ALOX5 (0.71) | PLCG2CSNK2A2CSNK2BCSNK2A1F2 | |
| SCHEMBL10602166 | 0.85 | ALDH1A1 (0.72) | PLCG2CSNK2A2CSNK2BCSNK2A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180943-A1 | Oxazolone analogs as amyloid aggregation inhibitors and for the treatment of alzheimer's disease and disorders related to amyloidosis | WARNER-LAMBERT COMPANY LLC | 2004-09-16 | — | — | US | claimed |
| CN-114127046-A | Fluorescence system for biological imaging and use thereof | 莱托克斯有限公司 | 2022-03-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180943-A1 | Oxazolone analogs as amyloid aggregation inhibitors and for the treatment of alzheimer's disease and disorders related to amyloidosis | APP, PSEN1, PSEN2 | PLCG2 4365/4885CSNK2A2 1982/4885CSNK2B 1874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.