Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NAT1 | P18440 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.55 |
| ▸ | CLK1 | P49759 | 1/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6789314 | 1.00 | ALDH1A1 (0.66) | ALDH1A1THRBMAPTNCOA3MEN1 | |
| SCHEMBL15863544 | 0.83 | AKR1B1 (0.65) | ALDH1A1MAPTMEN1KMT2ANAT1 | |
| SCHEMBL15869614 | 0.83 | AKR1B1 (0.65) | ALDH1A1MAPTMEN1KMT2ANAT1 | |
| SCHEMBL15863545 | 0.83 | AKR1B1 (0.65) | ALDH1A1MAPTMEN1KMT2ANAT1 | |
| SCHEMBL7962481 | 0.81 | CISD1 (0.68) | ALDH1A1MAPTMEN1KMT2ANAT1 | |
| SCHEMBL6785656 | 0.81 | CISD1 (0.68) | ALDH1A1MAPTMEN1KMT2ANAT1 | |
| SCHEMBL14407429 | 0.81 | MAPT (0.70) | ALDH1A1THRBMAPTNCOA3MAPK1 | |
| SCHEMBL30250046 | 0.81 | CISD1 (0.64) | ALDH1A1THRBMAPTNCOA3MEN1 | |
| SCHEMBL6784131 | 0.80 | CISD1 (0.67) | ALDH1A1MAPTMEN1KMT2ANAT1 | |
| SCHEMBL6784135 | 0.80 | CISD1 (0.67) | ALDH1A1MAPTMEN1KMT2ANAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727267-B2 | COMPOUND FOR USE IN THE TREATMENT OF VIRAL DISEASES | TULARIK INC. | 2004-04-27 | — | — | US | disclosed |
| US-20020142290-A1 | Compound for use in the treatment of viral diseases | TULARIK INC. (US) | 2002-10-03 | — | — | US | disclosed |
| WO-2001077091-A2 | NS5B HCV POLYMERASE INHIBITORS | TULARIK INC. (US) | 2001-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020142290-A1 | Compound for use in the treatment of viral diseases | POLRMT, RNASE1, POLI | ALDH1A1 854/4885THRB 2795/4885MAPT 1867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.