Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.56 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 10/20 | 0.39 |
| ▸ | HTR2A | P28223 | 9/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3481264 | 0.87 | PRKCI (0.58) | PRKCIBRPF1NTSR1HTR2CHTR2A | |
| SCHEMBL6609182 | 0.81 | PRKCI (0.51) | PRKCIBRPF1NTSR1HTR2CHTR2A | |
| SCHEMBL12967997 | 0.79 | PRKCI (0.53) | PRKCIBRPF1NTSR1HTR2CHTR2A | |
| SCHEMBL27593315 | 0.75 | PRKCI (0.45) | PRKCIBRPF1NTSR1HTR2CHTR2A | |
| SCHEMBL2976520 | 0.75 | SLC6A4 (0.46) | HTR2ASLC6A2SLC6A4 | |
| SCHEMBL30006940 | 0.72 | PRKCI (1.00) | PRKCIBRPF1CHEK1AURKADAPK3 | |
| SCHEMBL721707 | 0.72 | PRKCI (1.00) | PRKCIBRPF1CHEK1AURKADAPK3 | |
| SCHEMBL27658305 | 0.72 | NTSR1 (0.42) | PRKCIBRPF1NTSR1HTR2CCHEK1 | |
| SCHEMBL15712463 | 0.72 | PRKCI (0.44) | PRKCIBRPF1HTR2CHTR2AMAPK14 | |
| SCHEMBL2073701 | 0.71 | PRKCI (0.53) | PRKCIBRPF1NTSR1HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198733-A1 | Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198733-A1 | Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals | PER2, CNR2, DDC | PRKCI 1977/4885BRPF1 2819/4885NTSR1 772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.