Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301384 | 0.85 | ALDH1A1 (0.48) | ALDH1A1ALOX15IRAK4HTTSMN1; SMN2 | |
| SCHEMBL29930602 | 0.85 | ALDH1A1 (0.48) | ALDH1A1ALOX15IRAK4HTTSMN1; SMN2 | |
| SCHEMBL5744926 | 0.84 | KDM4E (0.51) | ALDH1A1ALOX15IRAK4HTTSMN1; SMN2 | |
| SCHEMBL7113007 | 0.82 | IRAK4 (0.64) | ALDH1A1IRAK4HTTLMNAKDM4E | |
| SCHEMBL2154267 | 0.78 | IRAK4 (0.68) | ALDH1A1ALOX15IRAK4LMNAKDM4E | |
| SCHEMBL5298178 | 0.77 | ALDH1A1 (0.53) | ALDH1A1ALOX15IRAK4HTTSMN1; SMN2 | |
| SCHEMBL10600901 | 0.76 | KMT2A (0.35) | ALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL3357655 | 0.74 | ALDH1A1 (0.52) | ALDH1A1ALOX15IRAK4HTTSMN1; SMN2 | |
| SCHEMBL2366561 | 0.74 | ALDH1A1 (0.44) | ALDH1A1ALOX15HTTSMN1; SMN2LMNA | |
| SCHEMBL16669782 | 0.72 | ALDH1A1 (0.50) | ALDH1A1ALOX15IRAK4HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040220409-A1 | Flecainide synthesis | MCDANIEL WILLIAM C | 2004-11-04 | — | — | US | claimed |
| WO-2002066413-A1 | FLECAINIDE SYNTHESIS | NARCHEM CORPORATION (US) | 2002-08-29 | — | — | WO | claimed |
| WO-2002066413-A1 | FLECAINIDE SYNTHESIS | NARCHEM CORPORATION (US) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220409-A1 | Flecainide synthesis | KCNH1, CYP3A43, CYP2F1 | ALDH1A1 450/4885ALOX15 809/4885IRAK4 4411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.