Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 3/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CD74 | P04233 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821095 | 0.85 | PLA2G2A (0.60) | KMT2ALMNAALDH1A1MEN1MAPT | |
| SCHEMBL6821169 | 0.84 | KMT2A (0.52) | KMT2ALMNAALDH1A1MEN1MAPT | |
| SCHEMBL679026 | 0.84 | KMT2A (0.64) | KMT2ALMNAALDH1A1MEN1MAPT | |
| SCHEMBL6820689 | 0.83 | PLA2G2A (0.68) | KMT2ALMNAALDH1A1MEN1MAPT | |
| SCHEMBL6820215 | 0.81 | KMT2A (0.52) | KMT2ALMNAALDH1A1MEN1MAPT | |
| SCHEMBL12357944 | 0.80 | CYP19A1 (0.70) | KMT2ALMNAALDH1A1MEN1MAPT | |
| SCHEMBL6823808 | 0.79 | MAPT (0.49) | KMT2ALMNAMEN1MAPTPKM | |
| SCHEMBL9271117 | 0.79 | KMT2A (0.53) | KMT2ALMNAALDH1A1MEN1MAPT | |
| SCHEMBL8358470 | 0.78 | KMT2A (0.72) | KMT2ALMNAALDH1A1MEN1MAPT | |
| SCHEMBL6927387 | 0.78 | KMT2A (0.55) | KMT2ALMNAALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |