Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPSE | Q9Y251 | 7/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735113 | 0.96 | GAA (0.43) | GAAHPSEACLYTP53KDR | |
| SCHEMBL7993931 | 0.89 | GAA (0.41) | GAAHPSETP53KDRMAPT | |
| SCHEMBL8001808 | 0.89 | GAA (0.42) | GAAHPSETP53KDRMAPT | |
| SCHEMBL7983540 | 0.89 | GAA (0.40) | GAAHPSETP53KDRMAPT | |
| SCHEMBL7994270 | 0.88 | GAA (0.39) | GAAHPSETP53KDRMAPT | |
| SCHEMBL7995977 | 0.87 | ACLY (0.39) | GAAHPSEACLYTP53KDR | |
| SCHEMBL7994435 | 0.84 | GAA (0.37) | GAATP53KDRMAPTRXFP1 | |
| SCHEMBL7994433 | 0.84 | GAA (0.37) | GAATP53KDRMAPTRXFP1 | |
| SCHEMBL7997959 | 0.84 | KDR (0.43) | HPSETP53KDRMAPTRXFP1 | |
| SCHEMBL5775077 | 0.83 | KDM4E (0.37) | TP53KDRMAPTRXFP1P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6703347-B2 | INSECTICIDES, FUNGICIDES, NEMATOCIDES, MOLLUSCICIDES, AND MITICIDES FOR PLANTS | SYNGENTA LIMITED (GB) | 2004-03-09 | — | — | US | disclosed |
| WO-2001055139-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |