Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735113 | 0.91 | GAA (0.43) | ACLYHPSEGAAMAPTSMN1; SMN2 | |
| SCHEMBL6790398 | 0.87 | GAA (0.50) | ACLYHPSEGAAMAPTTP53 | |
| SCHEMBL7993931 | 0.84 | GAA (0.41) | HPSEGAAMAPTSMN1; SMN2TP53 | |
| SCHEMBL8001808 | 0.83 | GAA (0.42) | HPSEGAAMAPTTP53KDR | |
| SCHEMBL7983540 | 0.83 | GAA (0.40) | HPSEGAAMAPTSMN1; SMN2TP53 | |
| SCHEMBL7995986 | 0.83 | MAPT (0.43) | MAPTSMN1; SMN2TP53RXFP1 | |
| SCHEMBL7994270 | 0.82 | GAA (0.39) | HPSEGAAMAPTSMN1; SMN2TP53 | |
| SCHEMBL1599472 | 0.81 | ACLY (0.40) | ACLYGAANPC1RAB9AMAPT | |
| SCHEMBL5735580 | 0.80 | ACLY (0.39) | ACLYGAANPC1RAB9AMAPT | |
| SCHEMBL5736818 | 0.80 | ACLY (0.39) | ACLYGAANPC1RAB9AAGPAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055139-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |