Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735113 | 0.86 | GAA (0.43) | KDM4EKDRTP53P2RY14RXFP1 | |
| SCHEMBL7998344 | 0.86 | PSMB5 (0.38) | KDM4EKDRTP53P2RY14RXFP1 | |
| SCHEMBL6790398 | 0.83 | GAA (0.50) | KDM4EKDRTP53P2RY14RXFP1 | |
| SCHEMBL7993931 | 0.81 | GAA (0.41) | KDM4EKDRTP53P2RY14RXFP1 | |
| SCHEMBL8001808 | 0.81 | GAA (0.42) | KDRTP53P2RY14RXFP1MAPT | |
| SCHEMBL7997959 | 0.81 | KDR (0.43) | KDM4EKDRTP53P2RY14RXFP1 | |
| SCHEMBL7983540 | 0.81 | GAA (0.40) | KDM4EKDRTP53P2RY14RXFP1 | |
| SCHEMBL7994270 | 0.80 | GAA (0.39) | KDM4EKDRTP53P2RY14RXFP1 | |
| SCHEMBL7978072 | 0.79 | ALDH1A1 (0.37) | TP53CSNK1DALDH1A1POLBHPGD | |
| SCHEMBL7997945 | 0.78 | SMN1; SMN2 (0.36) | KDM4ECSNK1DALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1686128-A2 | Isothiazole derivatives and their use as pesticides | Syngenta Limited (GB) | 2006-08-02 | — | — | EP | disclosed |