SCHEMBL6790879

SCHEMBL6790879

CN(c1cccc(F)c1F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.34
CES2 O00748 1/20 0.33
BCHE P06276 1/20 0.33
CES1 P23141 1/20 0.33
HSD11B1 P28845 1/20 0.32
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GPBAR1 Q8TDU6 1/20 0.32
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
MAT2A P31153 1/20 0.31
KCNH2 Q12809 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
PDK2 Q15119 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7690206 0.78 MAPT (0.46) RIPK1CES2BCHECES1KDM4E
SCHEMBL9287745 0.76 CES2 (0.37) RIPK1CES2BCHECES1KDM4E
SCHEMBL30076665 0.76 CES2 (0.37) RIPK1CES2BCHECES1KDM4E
SCHEMBL27969319 0.74 CES2 (0.35) RIPK1CES2BCHECES1KDM4E
SCHEMBL2093579 0.73 CES2 (0.36) RIPK1CES2BCHECES1KDM4E
SCHEMBL24316013 0.71 TAAR1 (0.34) RIPK1CES2BCHECES1KDM4E
SCHEMBL6790881 0.71 CES2 (0.38) RIPK1CES2BCHECES1KDM4E
SCHEMBL2455081 0.70 CES2 (0.39) CES2BCHECES1ACHE
SCHEMBL2093581 0.69 TDP1 (0.37) RIPK1CES2BCHECES1KDM4E
SCHEMBL22067643 0.69 CES2 (0.38) CES2BCHECES1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed