Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | PKM | P14618 | 3/20 | 0.68 |
| ▸ | MAOB | P27338 | 5/20 | 0.68 |
| ▸ | BCHE | P06276 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | SNCA | P37840 | 1/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29870504 | 1.00 | MAPT (0.68) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL6791116 | 1.00 | MAPT (0.68) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL12257967 | 0.87 | MAPT (0.90) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL9227394 | 0.85 | MAPT (0.70) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL8755683 | 0.85 | MAPT (0.70) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL4400320 | 0.82 | MAPT (1.00) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL977480 | 0.82 | MAPT (1.00) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL1604280 | 0.81 | MAPT (0.79) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL3012785 | 0.81 | MAOB (1.00) | MAPTLMNARAB9APKMMAOB | |
| SCHEMBL31436352 | 0.81 | MAPT (0.79) | MAPTLMNANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110756222-B | Nucleoside triphosphate artificial metalloenzyme and preparation and application thereof | 陕西师范大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-110756222-A | Nucleoside triphosphate artificial metalloenzyme and preparation and application thereof | 陕西师范大学 | 2020-02-07 | — | — | CN | disclosed |
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | MAPT 4795/4885LMNA 1239/4885NPC1 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.