SCHEMBL6791276

SCHEMBL6791276

CCCCN(C)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.35
DNM1 Q05193 3/20 0.33
ALDH1A1 P00352 2/20 0.32
ALDH2 P05091 1/20 0.32
AR P10275 1/20 0.31
KDM4E B2RXH2 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
GPR84 Q9NQS5 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6792391 0.91 DNM1 (0.46) DNM1GPR84
SCHEMBL5716300 0.90 TAS1R3 (0.32) MAPT
SCHEMBL5715687 0.85 DAO (0.31)
SCHEMBL5715810 0.82 DNM1 (0.39) DNM1GPR84
SCHEMBL5716435 0.78 CYP3A4 (0.33) MAPTALDH1A1ALDH2
SCHEMBL28085812 0.77 DNM1 (0.40) MAPTDNM1GPR84
SCHEMBL5715798 0.77 ALDH1A1 (0.38) ALDH1A1L3MBTL1
SCHEMBL7641630 0.74
SCHEMBL5547246 0.73
SCHEMBL5716608 0.73 DNM1 (0.41) MAPTDNM1ALDH1A1ALDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed