SCHEMBL6791610

SCHEMBL6791610

CN(C)c1ccc(-c2ccccc2C(=O)Nc2ccc(N(CCc3ccccn3)C(=O)OC(C)(C)C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMO Q99835 2/20 0.42
CYP3A4 P08684 5/20 0.42
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
GAA P10253 2/20 0.39
POLB P06746 1/20 0.39
ALDH1A1 P00352 3/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
CHRNB2 P17787 2/20 0.38
CHRNB4 P30926 2/20 0.38
CHRNA3 P32297 2/20 0.38
CHRNA4 P43681 2/20 0.38
MAPT P10636 2/20 0.37
NPC1 O15118 1/20 0.37
TP53 P04637 1/20 0.37
MAPK1 P28482 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6792911 0.94 SMO (0.47) SMOLMNAHTTGAAPOLB
SCHEMBL6795007 0.94 SMO (0.48) SMOCYP3A4LMNAHTTGAA
SCHEMBL6793636 0.93 SMO (0.42) SMOCYP3A4LMNAHTTGAA
SCHEMBL6799630 0.93 SMO (0.42) SMOCYP3A4LMNAHTTGAA
SCHEMBL6793251 0.93 SMO (0.42) SMOLMNAHTTGAAPOLB
SCHEMBL6800714 0.92 SMO (0.42) SMOLMNAHTTGAAPOLB
SCHEMBL6795221 0.92 CNR1 (0.43) SMOLMNAHTTGAAPOLB
SCHEMBL6788937 0.92 SMO (0.42) SMOLMNAHTTGAAPOLB
SCHEMBL6788159 0.92 SMO (0.43) SMOLMNAHTTGAAPOLB
SCHEMBL6791168 0.92 SMO (0.42) SMOLMNAHTTGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed
CN-1478077-A Benzamide compounds as APO B secretion inhibitors ����ҩƷ��ҵ��ʽ���� 2004-02-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 SMO 2094/4885CYP3A4 1229/4885LMNA 1239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.