SCHEMBL6795007

SCHEMBL6795007

CC(C)(C)OC(=O)N(CCc1ccccn1)c1ccc(NC(=O)c2ccccc2-c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMO Q99835 2/20 0.48
LMNA P02545 2/20 0.47
HTT P42858 2/20 0.47
GAA P10253 2/20 0.45
POLB P06746 1/20 0.45
ALDH1A1 P00352 1/20 0.45
CHRNB2 P17787 3/20 0.44
CHRNB4 P30926 3/20 0.44
CHRNA3 P32297 3/20 0.44
CHRNA4 P43681 3/20 0.44
KDM4E B2RXH2 1/20 0.39
TP53 P04637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
F2 P00734 1/20 0.38
NR1H4 Q96RI1 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6792911 0.98 SMO (0.47) SMOLMNAHTTGAAPOLB
SCHEMBL6791610 0.94 SMO (0.42) SMOLMNAHTTGAAPOLB
SCHEMBL6799630 0.94 SMO (0.42) SMOLMNAHTTGAAPOLB
SCHEMBL6793636 0.94 SMO (0.42) SMOLMNAHTTGAAPOLB
SCHEMBL6793251 0.94 SMO (0.42) SMOLMNAHTTGAAPOLB
SCHEMBL6788159 0.93 SMO (0.43) SMOLMNAHTTGAAPOLB
SCHEMBL6788937 0.93 SMO (0.42) SMOLMNAHTTGAAPOLB
SCHEMBL6800714 0.93 SMO (0.42) SMOLMNAHTTGAAPOLB
SCHEMBL6791168 0.93 SMO (0.42) SMOLMNAHTTGAAPOLB
SCHEMBL6795221 0.93 CNR1 (0.43) SMOLMNAHTTGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed
CN-1478077-A Benzamide compounds as APO B secretion inhibitors ����ҩƷ��ҵ��ʽ���� 2004-02-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 SMO 2094/4885LMNA 1239/4885HTT 2566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.