Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 1/20 | 0.51 |
| ▸ | CCKBR | P32239 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745190 | 0.92 | P2RY14 (0.54) | MTNR1AERAP2ERAP1LNPEPKMT2A | |
| SCHEMBL1129962 | 0.89 | P2RY14 (0.53) | MTNR1AERAP2ERAP1LNPEPKMT2A | |
| SCHEMBL17244051 | 0.82 | MTNR1A (0.62) | MTNR1AKMT2AALOX15ACEMAPT | |
| SCHEMBL29429300 | 0.82 | MTNR1A (0.62) | MTNR1AKMT2AALOX15ACEMAPT | |
| SCHEMBL29429324 | 0.82 | MTNR1A (0.62) | MTNR1AKMT2AALOX15ACEMAPT | |
| SCHEMBL29674779 | 0.82 | MTNR1A (0.62) | MTNR1AKMT2AALOX15ACEMAPT | |
| SCHEMBL29640391 | 0.82 | MTNR1A (0.62) | MTNR1AKMT2AALOX15ACEMAPT | |
| SCHEMBL29429295 | 0.81 | MTNR1A (0.61) | MTNR1AKMT2AALOX15ACEMAPT | |
| SCHEMBL29674872 | 0.81 | MTNR1A (0.61) | MTNR1AKMT2AALOX15ACEMAPT | |
| SCHEMBL3344871 | 0.81 | MC4R (0.55) | ERAP2ALOX15LMNAACEP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825354-B2 | OSTEOPOROSIS; RHEUMATIC DISEASES | WYETH HOLDINGS CORPORATION | 2004-11-30 | — | — | US | disclosed |