Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | MMP9 | P14780 | 2/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 4/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | P4HB | P07237 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.50 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745190 | 0.97 | P2RY14 (0.54) | P2RY14ALOX15KCNA5MMP2MMP9 | |
| SCHEMBL6791691 | 0.89 | CCKAR (0.51) | P2RY14ALOX15KCNA5MMP2MMP9 | |
| SCHEMBL3344871 | 0.89 | MC4R (0.55) | P2RY14ALOX15ACEP4HBERAP2 | |
| SCHEMBL7271569 | 0.89 | MC4R (0.55) | P2RY14ALOX15ACEP4HBERAP2 | |
| SCHEMBL17848778 | 0.85 | ACE (0.54) | P2RY14ALOX15ACEPOLBMEN1 | |
| SCHEMBL5805740 | 0.85 | ACE (0.54) | P2RY14ALOX15ACEPOLBMEN1 | |
| SCHEMBL3728145 | 0.83 | ALOX15 (0.70) | P2RY14ALOX15ACEPOLBMEN1 | |
| SCHEMBL13278205 | 0.83 | ALOX15 (0.70) | P2RY14ALOX15ACEPOLBMEN1 | |
| SCHEMBL6138173 | 0.83 | P2RY14 (0.56) | P2RY14ALOX15ACEPOLBMEN1 | |
| SCHEMBL29987387 | 0.83 | ALOX15 (0.70) | P2RY14ALOX15ACEPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282735-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MAKING THE SAME | Signum Biosciences, Inc. (US) | 2011-02-16 | — | — | EP | claimed |
| WO-2009132051-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MAKING THE SAME | SIGNUM BIOSCIENCES, INC. (US) | 2009-10-29 | — | — | WO | claimed |
| US-10583119-B2 | Compounds, compositions and methods for making the same | SIGNUM BIOSCIENCES, INC. (US) | 2020-03-10 | — | — | US | disclosed |
| US-20170266161-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MAKING THE SAME | SIGNUM BIOSCIENCES, INC. (US) | 2017-09-21 | — | — | US | disclosed |
| US-9486441-B2 | Compounds, compositions and methods for making the same | SIGNUM BIOSCIENCES, INC. (US) | 2016-11-08 | — | — | US | disclosed |
| EP-2282735-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MAKING THE SAME | Signum Biosciences, Inc. (US) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009132051-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MAKING THE SAME | SIGNUM BIOSCIENCES, INC. (US) | 2009-10-29 | — | — | WO | disclosed |
| US-20090264496-A1 | Compounds, Compositions and Methods for Making the Same | SIGNUM BIOSCIENCES, INC. | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264496-A1 | Compounds, Compositions and Methods for Making the Same | PPP2CA, PPP4C, PPP6C | P2RY14 4256/4885ALOX15 4125/4885KCNA5 3842/4885 |
| US-20170266161-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MAKING THE SAME | PPP2CA, PPP4C, PPP6C | P2RY14 4256/4885ALOX15 4125/4885KCNA5 3842/4885 |
| US-10583119-B2 | Compounds, compositions and methods for making the same | PPP2CA, PPP4C, PPP6C | P2RY14 4256/4885ALOX15 4125/4885KCNA5 3842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.