Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 14/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.79 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.78 |
| ▸ | MGLL | Q99685 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529558 | 0.88 | OPRD1 (1.00) | OPRD1OPRK1OPRM1 | |
| SCHEMBL8155338 | 0.87 | OPRD1 (0.77) | OPRD1OPRK1OPRM1 | |
| Hydrochloric Acid SCHEMBL6796562 | 0.86 | OPRD1 (0.98) | OPRD1OPRK1OPRM1 | |
| SCHEMBL8393489 | 0.86 | OPRD1 (0.78) | OPRD1OPRK1OPRM1MGLL | |
| Hydrochloric Acid SCHEMBL6792603 | 0.85 | OPRD1 (0.76) | OPRD1OPRK1OPRM1MGLL | |
| SCHEMBL8394427 | 0.82 | OPRD1 (1.00) | OPRD1OPRK1OPRM1 | |
| Hydrochloric Acid SCHEMBL6796030 | 0.81 | OPRD1 (0.98) | OPRD1OPRK1OPRM1 | |
| SCHEMBL15920046 | 0.80 | OPRD1 (0.68) | OPRD1OPRK1OPRM1MGLL | |
| SCHEMBL4936331 | 0.78 | OPRD1 (0.68) | OPRD1OPRK1OPRM1 | |
| Alcohol SCHEMBL29012312 | 0.78 | OPRD1 (0.62) | OPRD1OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138228-A1 | Novel compounds with analgesic effect | ASTRAZENECA CANADA INC. | 2004-07-15 | — | — | US | claimed |
| US-6680321-B1 | 4-((1-PIPERAZINYLMETHYL)-BENZAMIDE DERIVATIVES; HYPOTENSIVE AGENTS; IMMUNOMODULATORS | ASTRAZENECA CANADA, INC. (CA) | 2004-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138228-A1 | Novel compounds with analgesic effect | OPRL1, OPRK1, OPRM1 | OPRD1 4/4885OPRK1 2/4885OPRM1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.