Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796154 | 0.83 | KMT2A (0.62) | MEN1KMT2AMAPTTP53THRB | |
| SCHEMBL6796005 | 0.76 | POLB (0.32) | — | |
| SCHEMBL6796796 | 0.76 | ALDH1A1 (0.44) | MEN1KMT2AMAPTTP53THRB | |
| SCHEMBL16775234 | 0.69 | KMT2A (0.70) | MEN1KMT2AALDH1A1HPGDUSP2 | |
| SCHEMBL16759895 | 0.69 | KMT2A (0.70) | MEN1KMT2AALDH1A1HPGDUSP2 | |
| SCHEMBL16358149 | 0.69 | ATM (0.39) | MEN1KMT2AMAPTTP53ALDH1A1 | |
| SCHEMBL19971698 | 0.67 | MEN1 (0.54) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL19971697 | 0.67 | MEN1 (0.54) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL18517357 | 0.67 | MEN1 (0.54) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL796601 | 0.67 | KMT2A (0.62) | MEN1KMT2AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152905-A1 | Universal building blocks and support media for synthesis of oligonucleotides and their analogs | ISIS PHARMACEUTICALS, INC. | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152905-A1 | Universal building blocks and support media for synthesis of oligonucleotides and their analogs | POLM, POLRMT, POLB | MEN1 339/4885KMT2A 3124/4885CYP2D6 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.