Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792436 | 1.00 | ROCK2 (0.32) | ROCK2GRK2 | |
| SCHEMBL6787073 | 0.87 | ALDH1A1 (0.32) | ROCK2GRK2 | |
| SCHEMBL6786987 | 0.86 | ELANE (0.36) | — | |
| SCHEMBL6786990 | 0.86 | ELANE (0.36) | — | |
| SCHEMBL6793189 | 0.82 | CDK2 (0.35) | ROCK2GRK2 | |
| SCHEMBL1655455 | 0.81 | CDK2 (0.36) | ROCK2GRK2 | |
| SCHEMBL6793304 | 0.81 | KDM4C (0.37) | — | |
| Hydrochloric Acid SCHEMBL4257712 | 0.80 | CDK2 (0.36) | ROCK2GRK2 | |
| SCHEMBL1659385 | 0.80 | CDK2 (0.34) | ROCK2GRK2 | |
| Hydrochloric Acid SCHEMBL1658167 | 0.78 | CDK2 (0.42) | ROCK2GRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127492-A1 | Cyclic pyrazoles for the inhibition of mitogen activated protein kinase-activated protein kinase-2 | PHARMACIA CORPORATION | 2004-07-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127492-A1 | Cyclic pyrazoles for the inhibition of mitogen activated protein kinase-activated protein kinase-2 | MKNK2, MAPKAPK2, MAP3K2 | ROCK2 317/4885GRK2 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.