Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 14/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | RAD52 | P43351 | 3/20 | 0.54 |
| ▸ | GFER | P55789 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6882649 | 0.88 | KDM1A (0.62) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL18407155 | 0.86 | KDM1A (0.68) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL17154377 | 0.85 | KDM1A (0.62) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL6797100 | 0.80 | KMT2A (0.46) | KDM1AKMT2APOLBMEN1L3MBTL1 | |
| SCHEMBL18407160 | 0.78 | L3MBTL1 (0.60) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL17154450 | 0.77 | KDM1A (1.00) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL15673568 | 0.77 | KDM1A (1.00) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL17423377 | 0.77 | KDM1A (0.64) | KDM1AKMT2APOLBMEN1RAB9A | |
| SCHEMBL2127369 | 0.77 | ALDH1A1 (0.70) | KMT2AGFERMEN1L3MBTL1KDM4E | |
| SCHEMBL30998047 | 0.77 | ALDH1A1 (0.70) | KMT2AGFERMEN1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821983-B2 | INHIBITORS OF TOPOISOMERASE II CAN EXHIBIT ANTITUMOR ACTIVITY | ACADEMIA SINICA (TW) | 2004-11-23 | — | — | US | disclosed |
| US-20040198765-A1 | 5-(9-ACRIDINYLAMINO)-TOLUIDINE COMPOUNDS | ACADEMIA SINICA (TW) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198765-A1 | 5-(9-ACRIDINYLAMINO)-TOLUIDINE COMPOUNDS | DPP9, NANP, NAT1 | KDM1A 3382/4885KMT2A 2871/4885POLB 3433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.