SCHEMBL6792838

SCHEMBL6792838

O=C(Nc1ccc(NCCc2ccccn2)cc1)c1ccccc1Cc1cccc(C(F)(F)F)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 5/20 0.56
MEN1 O00255 4/20 0.56
MAPT P10636 4/20 0.56
KMT2A Q03164 4/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
ALDH1A1 P00352 2/20 0.56
LMNA P02545 2/20 0.56
HTT P42858 2/20 0.56
HPGD P15428 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
KDR P35968 2/20 0.45
ABL1 P00519 1/20 0.45
EGFR P00533 1/20 0.45
CSF1R P07333 1/20 0.45
PDGFRB P09619 1/20 0.45
KIT P10721 1/20 0.45
FLT1 P17948 1/20 0.45
FLT4 P35916 1/20 0.45
KDM4E B2RXH2 3/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6794696 0.93 MEN1 (0.48) RXFP1MEN1MAPTKMT2AL3MBTL1
SCHEMBL6791081 0.90 KDR (0.51) RXFP1MEN1MAPTKMT2AL3MBTL1
SCHEMBL6799387 0.83 RXFP1 (0.53) RXFP1MEN1MAPTKMT2AL3MBTL1
SCHEMBL6791003 0.82 RXFP1 (0.65) RXFP1MEN1MAPTKMT2AL3MBTL1
SCHEMBL6794451 0.81 RXFP1 (0.54) RXFP1MEN1MAPTKMT2AL3MBTL1
SCHEMBL6788926 0.80 KDR (0.53) MAPTKDRKDM4EGAAMTTP
SCHEMBL6491901 0.78 MTTP (0.64) MTTPAPOBSMO
SCHEMBL6788368 0.78 SMO (0.61) ALDH1A1LMNAHTTKDRMTTP
SCHEMBL6644249 0.77 SORT1 (0.47) RXFP1MEN1MAPTKMT2AL3MBTL1
SCHEMBL6488763 0.76 MTTP (0.51) RXFP1MEN1MAPTKMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 RXFP1 1420/4885MEN1 2426/4885MAPT 4795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.