SCHEMBL6793033

SCHEMBL6793033

O=C(NCCc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1)c1ccccn1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.52
SMO Q99835 1/20 0.51
GCGR P47871 1/20 0.49
GRM4 Q14833 3/20 0.48
CNR1 P21554 1/20 0.47
NAMPT P43490 1/20 0.47
KDR P35968 1/20 0.47
APOB P04114 2/20 0.47
MTTP P55157 1/20 0.47
TLR7 Q9NYK1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6796384 0.90 SMO (0.55) TRPV1SMOGRM4KDRAPOB
SCHEMBL6795714 0.88 TRPV1 (0.53) TRPV1SMOGRM4KDRAPOB
SCHEMBL6793203 0.86 TRPV1 (0.53) TRPV1SMOKDRAPOBMTTP
SCHEMBL6801341 0.84 SMO (0.61) TRPV1SMOKDRAPOBMTTP
SCHEMBL6791009 0.84 TRPV1 (0.55) TRPV1SMOKDRAPOBMTTP
SCHEMBL6788522 0.84 SMO (0.59) TRPV1SMONAMPTAPOBMTTP
SCHEMBL6788109 0.84 MTTP (0.56) APOBMTTP
SCHEMBL6788962 0.83 TRPV1 (0.52) TRPV1SMOGRM4KDRAPOB
SCHEMBL6793814 0.83 SMO (0.59) TRPV1SMOKDRAPOBMTTP
SCHEMBL7606603 0.82 CES1 (0.55) TRPV1SMOGRM4KDRAPOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 TRPV1 3714/4885SMO 2094/4885GCGR 688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.