Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8363701 | 1.00 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2MAPK1TDP1KMT2A | |
| SCHEMBL6793545 | 1.00 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2MAPK1TDP1KMT2A | |
| SCHEMBL23486912 | 0.86 | L3MBTL1 (0.67) | L3MBTL1SMN1; SMN2MAPK1TDP1MAPT | |
| SCHEMBL25489140 | 0.83 | TNF (0.64) | L3MBTL1SMN1; SMN2MAPK1TDP1MAPT | |
| SCHEMBL5045569 | 0.82 | LMNA (0.45) | L3MBTL1SMN1; SMN2MAPK1TDP1KMT2A | |
| SCHEMBL5177381 | 0.82 | LMNA (0.45) | L3MBTL1SMN1; SMN2MAPK1TDP1KMT2A | |
| SCHEMBL8363638 | 0.81 | SMN1; SMN2 (0.50) | L3MBTL1SMN1; SMN2MAPK1TDP1KMT2A | |
| SCHEMBL10054644 | 0.81 | SMN1; SMN2 (0.50) | L3MBTL1SMN1; SMN2MAPK1TDP1KMT2A | |
| Hydrochloric Acid SCHEMBL5045565 | 0.81 | MAOB (0.45) | L3MBTL1SMN1; SMN2MAPK1TDP1KMT2A | |
| Hydrochloric Acid SCHEMBL5045567 | 0.81 | MAOB (0.45) | L3MBTL1SMN1; SMN2MAPK1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082585-A1 | Prodrugs of substituted polycyclic compounds useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082585-A1 | Prodrugs of substituted polycyclic compounds useful for selective inhibition of the coagulation cascade | TFPI, F2, PLG | L3MBTL1 1399/4885SMN1; SMN2 4186/4885MAPK1 1730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.