SCHEMBL679369

SCHEMBL679369

Nc1ccc(CCOC(=O)/C=C/c2ccc(OC(=O)c3ccc(OCCCC(F)(F)C(F)(F)C(F)(F)F)cc3)cc2)c(N)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MET P08581 10/20 0.37
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
CA4 P22748 3/20 0.37
CA9 Q16790 3/20 0.37
CA6 P23280 2/20 0.37
CA5A P35218 2/20 0.37
CA7 P43166 2/20 0.37
CA14 Q9ULX7 2/20 0.37
CA5B Q9Y2D0 2/20 0.37
ALOX5 P09917 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
CYP1A1 P04798 1/20 0.35
CYP1B1 Q16678 1/20 0.35
LMNA P02545 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CA2 P00918 1/20 0.34
PPARA Q07869 2/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL678510 0.95 MET (0.38) METCA12CA1CA4CA9
SCHEMBL15772156 0.95 MET (0.38) METCA12CA1CA4CA9
SCHEMBL2141780 0.93 CA12 (0.37) METCA12CA1CA4CA9
SCHEMBL28658287 0.93 MAPT (0.37) METCA12CA1CA4CA9
SCHEMBL2141562 0.93 MAPT (0.37) METCA12CA1CA4CA9
SCHEMBL13720132 0.92 CA12 (0.41) METCA12CA1CA4CA9
SCHEMBL679824 0.92 CA12 (0.41) METCA12CA1CA4CA9
SCHEMBL1564685 0.92 CA12 (0.41) METCA12CA1CA4CA9
SCHEMBL1974146 0.92 CA12 (0.41) METCA12CA1CA4CA9
SCHEMBL2136678 0.91 MET (0.38) METCA12CA1CA4CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11053354-B2 Liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2021-07-06 US disclosed
US-20170362381-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2017-12-21 US disclosed
US-20170362381-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2017-12-21 US disclosed
US-9684207-B2 Polymer for alignment films, and liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2017-06-20 US disclosed
US-9684207-B2 Polymer for alignment films, and liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2017-06-20 US disclosed
US-9541797-B2 Liquid crystal display device and method for producing same UNIFIED INNOVATIVE TECHNOLOGY, LLC (US) 2017-01-10 US disclosed
US-9541797-B2 Liquid crystal display device and method for producing same UNIFIED INNOVATIVE TECHNOLOGY, LLC (US) 2017-01-10 US disclosed
EP-1966119-B1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2016-10-19 EP disclosed
US-9239493-B2 Liquid crystal alignment agent, liquid crystal display, and method for manufacturing liquid crystal display SHARP KABUSHIKI KAISHA (JP) 2016-01-19 US disclosed
US-9239493-B2 Liquid crystal alignment agent, liquid crystal display, and method for manufacturing liquid crystal display SHARP KABUSHIKI KAISHA (JP) 2016-01-19 US disclosed
EP-2305632-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-06 EP disclosed
EP-2305632-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-06 EP disclosed
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2011-03-17 US disclosed
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2011-03-17 US disclosed
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2011-03-17 US disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed
WO-2008135131-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2008-11-13 WO disclosed
EP-1860094-A1 Photocrosslinkable materials Rolic AG (CH) 2007-11-28 EP disclosed
WO-2007071091-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2007-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293888-A1 Photocrosslinkable Materials DDC, PARG, ALAD MET 4434/4885CA12 1753/4885CA1 705/4885
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS PARG, PARN, PUF60 MET 4377/4885CA12 744/4885CA1 233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.