SCHEMBL679372

SCHEMBL679372

Nc1ccc(-c2ccc(N)cc2COC(=O)/C=C/c2ccc(OC(=O)c3ccc(OCCCC(F)(F)F)cc3)cc2)c(COC(=O)/C=C/c2ccc(OC(=O)c3ccc(OCCCC(F)(F)F)cc3)cc2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 3/20 0.40
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
CYP1A1 P04798 2/20 0.38
CYP1B1 Q16678 2/20 0.38
PPARA Q07869 2/20 0.36
ESR1 P03372 2/20 0.36
APP P05067 1/20 0.36
PRSS1 P07477 1/20 0.35
ACR P10323 1/20 0.35
MAOB P27338 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30086264 1.00 ABCG2 (0.40) ABCG2CA12CA1CA4CA6
SCHEMBL18112629 1.00 ABCG2 (0.40) ABCG2CA12CA1CA4CA6
SCHEMBL679305 0.93 MAPT (0.39) ABCG2CA12CA1CA4CA6
SCHEMBL21974541 0.93 SAE1 (0.38) ABCG2CA12CA1CA4CA6
SCHEMBL18993099 0.92 ABCG2 (0.35) ABCG2CA12CA1CA4CA6
SCHEMBL14019209 0.92 KMT2A (0.43) ABCG2CA12CA1CA4CA9
SCHEMBL3634719 0.92 ABCG2 (0.39) ABCG2CA12CA1CA4CA6
SCHEMBL2136229 0.92 ABCG2 (0.39) ABCG2CA12CA1CA4CA6
SCHEMBL13829579 0.92 ABCG2 (0.39) ABCG2CA12CA1CA4CA6
SCHEMBL15771844 0.91 ABCG2 (0.34) ABCG2CA12CA1CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024125945-A1 COMPOSITION FOR FORMING A LIQUID CRYSTAL ALIGNMENT FILM Rolic Technologies AG (CH) 2024-06-20 WO disclosed
WO-2023032784-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2023-03-09 WO disclosed
US-11561440-B2 Photoalignment composition for the stabilization of the pre-tilt angle in liquid crystal layers Rolic Technologies AG (CH) 2023-01-24 US disclosed
US-11561440-B2 Photoalignment composition for the stabilization of the pre-tilt angle in liquid crystal layers Rolic Technologies AG (CH) 2023-01-24 US disclosed
EP-3628054-B1 NEW PHOTOALIGNMENT COMPOSITION FOR THE STABILIZATION OF THE PRE-TILT ANGLE IN LIQUID CRYSTAL LAYERS ROLIC TECH AG (CH) 2021-10-06 EP disclosed
EP-3628054-B1 NEW PHOTOALIGNMENT COMPOSITION FOR THE STABILIZATION OF THE PRE-TILT ANGLE IN LIQUID CRYSTAL LAYERS ROLIC TECH AG (CH) 2021-10-06 EP disclosed
US-11053354-B2 Liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2021-07-06 US disclosed
EP-3107978-B1 LIQUID CRYSTAL ALIGNMENT COMPOSITION, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT ROLIC TECH AG (CH) 2020-05-06 EP disclosed
EP-3107978-B1 LIQUID CRYSTAL ALIGNMENT COMPOSITION, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT ROLIC TECH AG (CH) 2020-05-06 EP disclosed
EP-3628054-A2 NEW PHOTOALIGNMENT COMPOSITION FOR THE STABILIZATION OF THE PRE-TILT ANGLE IN LIQUID CRYSTAL LAYERS Rolic Technologies AG (CH) 2020-04-01 EP disclosed
EP-2308827-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-13 EP disclosed
EP-2305632-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-06 EP disclosed
EP-2305631-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-06 EP disclosed
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2011-03-17 US disclosed
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2011-03-17 US disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed
WO-2008135131-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2008-11-13 WO disclosed
EP-1860094-A1 Photocrosslinkable materials Rolic AG (CH) 2007-11-28 EP disclosed
WO-2007071091-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2007-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293888-A1 Photocrosslinkable Materials DDC, PARG, ALAD ABCG2 4577/4885CA12 1753/4885CA1 705/4885
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS PARG, PARN, PUF60 ABCG2 3643/4885CA12 744/4885CA1 233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.