Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796669 | 0.79 | CYP19A1 (0.54) | CYP19A1TRPM8CA12CA2CA9 | |
| SCHEMBL6798926 | 0.79 | CYP19A1 (0.49) | CYP19A1CA12CA2CA3CA6 | |
| SCHEMBL6802215 | 0.76 | CYP19A1 (0.58) | CYP19A1CA12CA2CA3CA6 | |
| SCHEMBL6797228 | 0.76 | ESR1 (0.61) | CYP19A1CA12CA2CA3CA6 | |
| SCHEMBL3611701 | 0.75 | NSD2 (0.54) | NSD2NSD3TRPM8MEN1USP2 | |
| SCHEMBL6800779 | 0.74 | MEN1 (0.55) | CYP19A1NSD2NSD3MEN1USP2 | |
| SCHEMBL6801305 | 0.74 | CYP19A1 (0.55) | CYP19A1CA12CA2CA3CA6 | |
| SCHEMBL150285 | 0.72 | CYP2C19 (0.58) | MEN1KMT2AALDH1A1CNR2KDM1A | |
| SCHEMBL6802968 | 0.71 | CYP19A1 (0.56) | CYP19A1CA12CA2CA3CA6 | |
| SCHEMBL28677901 | 0.71 | LOXL2 (0.46) | NSD2NSD3TRPM8ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308297-C | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2007-04-04 | — | — | CN | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| CN-1360570-A | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2002-07-24 | — | — | CN | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |