Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.72 |
| ▸ | CA1 | P00915 | 12/20 | 0.72 |
| ▸ | CA9 | Q16790 | 12/20 | 0.72 |
| ▸ | CA12 | O43570 | 11/20 | 0.72 |
| ▸ | STS | P08842 | 3/20 | 0.64 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.59 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806188 | 0.92 | CA1 (0.68) | CA2CA1CA9CA12STS | |
| SCHEMBL6798913 | 0.87 | STS (0.61) | CA2CA1CA9CA12STS | |
| SCHEMBL6801137 | 0.85 | CA1 (0.76) | CA2CA1CA9CA12STS | |
| SCHEMBL6798469 | 0.84 | STS (0.77) | CA2CA1CA9CA12STS | |
| SCHEMBL6800282 | 0.82 | CA1 (0.67) | CA2CA1CA9CA12ENPP3 | |
| SCHEMBL6795691 | 0.81 | CA1 (0.78) | CA2CA1CA9CA12STS | |
| SCHEMBL6802877 | 0.81 | CA12 (0.56) | CA2CA1CA9CA12STS | |
| SCHEMBL6801257 | 0.81 | STS (0.65) | CA2CA1CA9CA12STS | |
| SCHEMBL6798465 | 0.80 | CA9 (0.78) | CA2CA1CA9CA12MEN1 | |
| SCHEMBL2237057 | 0.79 | CA2 (0.74) | CA2CA1CA9CA12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |