Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.67 |
| ▸ | CA2 | P00918 | 6/20 | 0.67 |
| ▸ | CA9 | Q16790 | 6/20 | 0.67 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.66 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.66 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.66 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.62 |
| ▸ | KIF11 | P52732 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | RORC | P51449 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806188 | 0.90 | CA1 (0.68) | CA1CA2CA9NPC1RAB9A | |
| SCHEMBL6801137 | 0.83 | CA1 (0.76) | CA1CA2CA9NPC1RAB9A | |
| SCHEMBL6793945 | 0.82 | CA2 (0.72) | CA1CA2CA9ENPP3ENPP1 | |
| SCHEMBL6798469 | 0.82 | STS (0.77) | CA1CA2CA9NPC1RAB9A | |
| SCHEMBL7513604 | 0.82 | TRPV1 (0.83) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL9451383 | 0.82 | CA2 (1.00) | CA1CA2CA9KIF11KMT2A | |
| SCHEMBL4043267 | 0.80 | CA2 (0.96) | CA1CA2CA9KIF11KMT2A | |
| SCHEMBL6795691 | 0.80 | CA1 (0.78) | CA1CA2CA9NPC1RAB9A | |
| SCHEMBL6798465 | 0.78 | CA9 (0.78) | CA1CA2CA9NPC1RAB9A | |
| SCHEMBL17222457 | 0.77 | NPC1 (0.59) | CA1CA2ENPP3ENPP1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |