Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 14/20 | 0.76 |
| ▸ | CA2 | P00918 | 14/20 | 0.76 |
| ▸ | CA9 | Q16790 | 13/20 | 0.76 |
| ▸ | CA12 | O43570 | 10/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | STS | P08842 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806188 | 0.92 | CA1 (0.68) | CA1CA2CA9CA12STS | |
| SCHEMBL6793945 | 0.85 | CA2 (0.72) | CA1CA2CA9CA12STS | |
| SCHEMBL6798469 | 0.84 | STS (0.77) | CA1CA2CA9CA12MAPT | |
| SCHEMBL6800282 | 0.83 | CA1 (0.67) | CA1CA2CA9CA12MAPT | |
| SCHEMBL6795691 | 0.82 | CA1 (0.78) | CA1CA2CA9CA12MAPT | |
| SCHEMBL3669771 | 0.81 | PGR (0.67) | MAPTMEN1KMT2ANPC1TP53 | |
| SCHEMBL6798465 | 0.81 | CA9 (0.78) | CA1CA2CA9CA12MAPT | |
| SCHEMBL21798720 | 0.80 | KMT2A (0.76) | MAPTMEN1KMT2ANPC1TP53 | |
| SCHEMBL3679372 | 0.80 | KMT2A (0.76) | MAPTMEN1KMT2ANPC1TP53 | |
| SCHEMBL6806486 | 0.79 | KMT2A (0.59) | CA1CA2CA9CA12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |