Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426443 | 0.92 | KDM1A (0.53) | KDM1AKDM1BKMT2AMEN1NPC1 | |
| SCHEMBL1782899 | 0.85 | TP53 (0.44) | TP53RECQLMAPTGAAKMT2A | |
| SCHEMBL7683113 | 0.84 | TP53 (0.51) | TP53RECQLMAPTGAAKMT2A | |
| SCHEMBL7685976 | 0.82 | TP53 (0.42) | TP53RECQLMAPTGAAKMT2A | |
| SCHEMBL6794592 | 0.82 | SLC9A1 (0.43) | TP53RECQLMAPTGAACA1 | |
| SCHEMBL6796450 | 0.82 | TP53 (0.59) | TP53RECQLMAPTGAAKMT2A | |
| SCHEMBL6804449 | 0.81 | KDM1A (0.54) | KDM1AKDM1BKMT2AMEN1NPC1 | |
| SCHEMBL1782611 | 0.79 | TP53 (0.42) | TP53RECQLMAPTGAAKMT2A | |
| SCHEMBL11824957 | 0.79 | TP53 (0.59) | TP53RECQLMAPTGAA | |
| SCHEMBL30368483 | 0.79 | TP53 (0.42) | TP53RECQLMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706732-B1 | PROPHYLACTIC AND THERAPEUTIC EFFECT ON MYOCARDIAL INFARCTION AND ACCOMPANYING DYSFUNCTIONS, ARRHYTHMIA, UNSTABLE ANGINA, CARDIAC HYPERTROPHY, ETC.; SODIUM-PROTON EXCHANGE INHIBITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-03-16 | — | — | US | disclosed |
| EP-1182194-A1 | PERNASAL PREPARATIONS | Takeda Chemical Industries, Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |