Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426443 | 0.88 | KDM1A (0.53) | KDM1AKDM1BDPP4MEN1NPC1 | |
| SCHEMBL7687326 | 0.85 | HTR2A (0.38) | KDM1AKDM1BCHRNB2CHRNA4 | |
| SCHEMBL6794027 | 0.81 | KDM1A (0.46) | KDM1AKDM1BDPP4MEN1NPC1 | |
| SCHEMBL7679054 | 0.80 | HTR2C (0.45) | — | |
| SCHEMBL28255706 | 0.74 | HCAR2 (0.46) | KDM1AKDM1BDPP4MEN1NPC1 | |
| SCHEMBL18792912 | 0.72 | KDM1A (0.49) | KDM1AKDM1BDPP4DPP8DPP9 | |
| SCHEMBL1754910 | 0.72 | KDM1A (0.49) | KDM1AKDM1BDPP4DPP8DPP9 | |
| SCHEMBL15566855 | 0.72 | KDM1A (0.55) | KDM1AKDM1BHCAR2CHRNB2CHRNB4 | |
| SCHEMBL12958096 | 0.70 | SLC9A1 (0.45) | KDM1AKDM1BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL11773147 | 0.69 | KDM1A (0.52) | KDM1AKDM1BMEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706732-B1 | PROPHYLACTIC AND THERAPEUTIC EFFECT ON MYOCARDIAL INFARCTION AND ACCOMPANYING DYSFUNCTIONS, ARRHYTHMIA, UNSTABLE ANGINA, CARDIAC HYPERTROPHY, ETC.; SODIUM-PROTON EXCHANGE INHIBITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-03-16 | — | — | US | disclosed |
| EP-1182194-A1 | PERNASAL PREPARATIONS | Takeda Chemical Industries, Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |