Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.54 |
| ▸ | PHGDH | O43175 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27583336 | 1.00 | ACACB (0.57) | ACACBALDH1A1KDRPHGDHKMT2A | |
| SCHEMBL6789222 | 1.00 | ACACB (0.57) | ACACBALDH1A1KDRPHGDHKMT2A | |
| SCHEMBL28596532 | 0.82 | MEN1 (0.61) | ALDH1A1KDRPHGDHKMT2AMEN1 | |
| SCHEMBL6795144 | 0.81 | ACACB (0.61) | ACACBALDH1A1KDRPHGDHLMNA | |
| SCHEMBL6792182 | 0.81 | ACACB (0.61) | ACACBALDH1A1KDRPHGDHLMNA | |
| SCHEMBL27583365 | 0.81 | ACACB (0.61) | ACACBALDH1A1KDRPHGDHLMNA | |
| SCHEMBL31739150 | 0.79 | ACACB (0.69) | ACACBALDH1A1PHGDHKMT2AMEN1 | |
| SCHEMBL16592576 | 0.78 | KDR (0.81) | KDRKMT2AMEN1MAPTSNCA | |
| SCHEMBL31739129 | 0.78 | PDE2A (0.61) | ACACB | |
| SCHEMBL4929872 | 0.77 | AMY1A (0.60) | ALDH1A1PHGDHKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
| CN-1478077-A | Benzamide compounds as APO B secretion inhibitors | ����ҩƷ��ҵ��ʽ���� | 2004-02-25 | — | — | CN | disclosed |
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | ACACB 104/4885ALDH1A1 1427/4885KDR 3180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.