Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 10/20 | 0.50 |
| ▸ | MMP2 | P08253 | 7/20 | 0.47 |
| ▸ | MMP9 | P14780 | 7/20 | 0.47 |
| ▸ | MMP8 | P22894 | 5/20 | 0.47 |
| ▸ | MMP1 | P03956 | 5/20 | 0.45 |
| ▸ | MMP3 | P08254 | 5/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784051 | 0.89 | MMP2 (0.52) | MMP13MMP2MMP9MMP8MMP1 | |
| SCHEMBL6794468 | 0.88 | MMP2 (0.47) | MMP13MMP2MMP9MMP8MMP1 | |
| SCHEMBL6789191 | 0.86 | MMP13 (0.47) | MMP13MMP2MMP9MMP8MMP1 | |
| SCHEMBL6789136 | 0.80 | KMT2A (0.50) | MMP13MMP2MMP9MMP8MMP1 | |
| SCHEMBL6788890 | 0.80 | BCL2L1 (0.49) | MMP13MMP2MMP9MMP8MMP1 | |
| SCHEMBL6790233 | 0.79 | MMP2 (0.45) | MMP13MMP2MMP9MMP8MMP1 | |
| SCHEMBL6783118 | 0.76 | MMP2 (0.62) | MMP13MMP2MMP9MMP8MMP1 | |
| SCHEMBL6796186 | 0.76 | MMP2 (0.62) | MMP13MMP2MMP9MMP8MMP1 | |
| SCHEMBL6783185 | 0.76 | MMP2 (0.62) | MMP13MMP2MMP9MMP8MMP1 | |
| SCHEMBL6789365 | 0.76 | KMT2A (0.48) | MMP13MMP2MMP9MMP8MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6765003-B1 | ANTICARCINOGENIC, ANTITUMOR, AND ANTIMETASTASIS AGENTS; RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, OSTEOPOROSIS, MULTIPLE SCLEROSIS, STROKE, ARTERIOSCLEROSIS, | PHARMACIA ITALIA, SPA (IT) | 2004-07-20 | — | — | US | disclosed |