Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.47 |
| ▸ | MMP9 | P14780 | 8/20 | 0.47 |
| ▸ | MMP3 | P08254 | 7/20 | 0.47 |
| ▸ | MMP13 | P45452 | 6/20 | 0.47 |
| ▸ | MMP1 | P03956 | 5/20 | 0.47 |
| ▸ | MMP8 | P22894 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 3/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MMP7 | P09237 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6794449 | 0.88 | MMP13 (0.50) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL6796186 | 0.88 | MMP2 (0.62) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL6783185 | 0.88 | MMP2 (0.62) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL6783118 | 0.88 | MMP2 (0.62) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL19506062 | 0.87 | MMP13 (0.46) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL6788239 | 0.84 | MMP3 (0.46) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL6787522 | 0.78 | MMP2 (0.54) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL6789717 | 0.78 | MMP2 (0.51) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL6794038 | 0.78 | BCL2L1 (0.47) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL6790742 | 0.77 | KMT2A (0.53) | MMP2MMP9MMP3MMP1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6765003-B1 | ANTICARCINOGENIC, ANTITUMOR, AND ANTIMETASTASIS AGENTS; RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, OSTEOPOROSIS, MULTIPLE SCLEROSIS, STROKE, ARTERIOSCLEROSIS, | PHARMACIA ITALIA, SPA (IT) | 2004-07-20 | — | — | US | disclosed |