Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MELK | Q14680 | 5/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866469 | 0.76 | MEN1 (0.55) | ALDH1A1LMNANPSR1MEN1KMT2A | |
| SCHEMBL9865539 | 0.76 | ALDH1A1 (0.54) | ALDH1A1LMNANPSR1MEN1KMT2A | |
| SCHEMBL9864903 | 0.75 | ALDH1A1 (0.50) | ALDH1A1LMNANPSR1MEN1KMT2A | |
| SCHEMBL9865502 | 0.72 | ALDH1A1 (0.43) | ALDH1A1LMNANPSR1MEN1KMT2A | |
| SCHEMBL3401686 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL9865266 | 0.70 | L3MBTL1 (0.51) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL9865195 | 0.70 | LMNA (0.52) | ALDH1A1LMNANPSR1MEN1KMT2A | |
| SCHEMBL2134104 | 0.68 | MELK (0.62) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL9865163 | 0.67 | MAPT (0.40) | ALDH1A1LMNANPSR1MEN1KMT2A | |
| SCHEMBL6789033 | 0.66 | MAPT (0.43) | ALDH1A1LMNANPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1521165-A | Thiophene derivative | 拜尔农作物科学股份公司 | 2004-08-18 | — | — | CN | disclosed |
| WO-2004067527-A1 | THIOPHENE DERIVATIVES AS MICROBICIDES AND HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2004-08-12 | — | — | WO | disclosed |