SCHEMBL6794742

SCHEMBL6794742

CN(C(=O)OC(C)(C)C)c1nc(CCO)cs1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
PAX8 Q06710 1/20 0.36
GSTO1 P78417 1/20 0.33
UCHL1 P09936 3/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
LMNA P02545 1/20 0.33
SCD O00767 2/20 0.32
USP30 Q70CQ3 3/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
PTPRB P23467 2/20 0.31
GBA1 P04062 1/20 0.31
PI4KB Q9UBF8 1/20 0.31
SSTR4 P31391 1/20 0.31
CFTR P13569 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27583367 0.85 KMT2A (0.41) MEN1KMT2APAX8GSTO1UCHL1
SCHEMBL28302436 0.85 MEN1 (0.40) MEN1KMT2APAX8GSTO1UCHL1
SCHEMBL15709828 0.84 MEN1 (0.46) MEN1KMT2APAX8GSTO1UCHL1
SCHEMBL28302432 0.83 MEN1 (0.45) MEN1KMT2APAX8GSTO1UCHL1
SCHEMBL15709971 0.82 MEN1 (0.50) MEN1KMT2APAX8GAAMAPT
SCHEMBL19820663 0.80 MEN1 (0.68) MEN1KMT2AGAAMAPTLMNA
SCHEMBL23662174 0.79 PAX8 (0.40) MEN1KMT2APAX8GSTO1UCHL1
SCHEMBL31596356 0.77 PAX8 (0.39) MEN1KMT2APAX8GSTO1UCHL1
SCHEMBL6794653 0.77 PSMD10 (0.35) MEN1KMT2AMAPTLMNANPC1
SCHEMBL20387999 0.76 MEN1 (0.40) MEN1KMT2APAX8GSTO1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 MEN1 2426/4885KMT2A 2457/4885PAX8 4664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.