SCHEMBL6794970

SCHEMBL6794970

Cc1cc(C(F)(F)F)cc(CO)n1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
TACR1 P25103 2/20 0.36
NOTUM Q6P988 2/20 0.36
SRC P12931 1/20 0.36
CDK2 P24941 1/20 0.36
ZAP70 P43403 1/20 0.36
SYK P43405 1/20 0.36
POLQ O75417 2/20 0.35
FBP1 P09467 1/20 0.35
KMT2A Q03164 1/20 0.34
GAA P10253 2/20 0.33
SORT1 Q99523 1/20 0.33
AGBL2 Q5U5Z8 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12585927 0.82 NOS3 (0.38) HSP90AA1HSP90AB1POLQ
SCHEMBL18352285 0.81 HSP90AA1 (0.40) HSP90AA1HSP90AB1NOTUMPOLQ
Hydrochloric Acid SCHEMBL29351155 0.79 HSP90AA1 (0.39) HSP90AA1HSP90AB1NOTUMPOLQ
SCHEMBL10025587 0.79 HSP90AA1 (0.46) HSP90AA1HSP90AB1GAASORT1
SCHEMBL18560881 0.78 HSP90AA1 (0.38) HSP90AA1HSP90AB1POLQKMT2A
SCHEMBL21907306 0.78 NOS1 (0.37) HSP90AA1HSP90AB1TACR1KMT2A
SCHEMBL17396687 0.78 HTT (0.50) HSP90AA1HSP90AB1TACR1POLQKMT2A
SCHEMBL18379218 0.77 TACR1 (0.40) TACR1NOTUMGAA
SCHEMBL30092277 0.77 TACR1 (0.40) TACR1NOTUMGAA
SCHEMBL12874041 0.75 CACNA1H (0.43) HSP90AA1HSP90AB1POLQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040116480-A1 Oxime ether compound and agricultural or horticultural bactericide NIPPON SODA CO., LTD. (JP) 2004-06-17 US disclosed
EP-1362850-A1 OXIME ETHER COMPOUND AND AGRICULTURAL OR HORTICULTURAL BACTERICIDE NIPPON SODA CO., LTD. (JP) 2003-11-19 EP disclosed