Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | BCL2 | P10415 | 5/20 | 0.46 |
| ▸ | BCL2L2 | Q92843 | 5/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16656338 | 0.80 | ALDH1A1 (0.49) | SMN1; SMN2BCL2BCL2L2MCL1ALDH1A1 | |
| SCHEMBL6937699 | 0.80 | ALDH1A1 (0.40) | ALDH1A1GAA | |
| SCHEMBL11616001 | 0.79 | ALDH1A1 (0.64) | BCL2BCL2L2ALDH1A1GAA | |
| SCHEMBL4609039 | 0.79 | ALDH1A1 (0.64) | BCL2BCL2L2ALDH1A1GAA | |
| SCHEMBL478909 | 0.79 | ALDH1A1 (0.64) | BCL2BCL2L2ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7473828 | 0.78 | ALDH1A1 (0.39) | ALDH1A1GAA | |
| SCHEMBL15623808 | 0.77 | ALDH1A1 (0.53) | SMN1; SMN2BCL2BCL2L2MCL1ALDH1A1 | |
| SCHEMBL9327777 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2BCL2BCL2L2MCL1RNPEP | |
| SCHEMBL29901248 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2BCL2BCL2L2MCL1ALDH1A1 | |
| SCHEMBL21449404 | 0.75 | BCL2 (0.45) | BCL2BCL2L2MCL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014652-A1 | Tumor activated prodrug compounds and methods of making and using the same | DIATOS SA (FR) | 2004-01-22 | — | — | US | disclosed |
| EP-1286700-A2 | TUMOR ACTIVATED PRODRUG COMPOUNDS | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001091798-A2 | TUMOR ACTIVATED PRODRUG COMPOUNDS | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2001-12-06 | — | — | WO | disclosed |