SCHEMBL6795346

SCHEMBL6795346

O=C(Nc1ccc(OCCc2ccccn2)c(F)c1)c1ccccc1-c1ccc(C(F)(F)F)cc1

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SMO Q99835 3/20 0.59
TP53 P04637 1/20 0.47
MTTP P55157 8/20 0.47
APOB P04114 7/20 0.47
GAA P10253 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TRPV1 Q8NER1 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6789743 0.90 SMO (0.58) SMOMTTPAPOBGAASMN1; SMN2
SCHEMBL6789334 0.88 SMO (0.56) SMOMTTPAPOBGAASMN1; SMN2
SCHEMBL6792614 0.88 SMO (0.55) SMOMTTPAPOBGAASMN1; SMN2
SCHEMBL6793327 0.86 SMO (0.59) SMOMTTPAPOBGAATRPV1
SCHEMBL6794869 0.86 SMO (0.56) SMOMTTPAPOBTRPV1
SCHEMBL6792904 0.84 SMO (0.61) SMOTP53MTTPAPOBTRPV1
SCHEMBL6788361 0.82 SMO (0.56) SMOMTTPAPOBTRPV1
SCHEMBL6799155 0.82 SMO (0.57) SMOTP53MTTPAPOBTRPV1
SCHEMBL6492227 0.82 SMO (0.49) SMOMTTPAPOBGAASMN1; SMN2
SCHEMBL6801341 0.81 SMO (0.61) SMOMTTPAPOBSMN1; SMN2TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed
EP-1326835-A1 BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-07-16 EP disclosed
WO-2002028835-A1 BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-04-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 SMO 2094/4885TP53 4865/4885MTTP 363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.