Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA4 | P22748 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL7214154 | 0.97 | CA4 (0.48) | CA1CA4CA5ACA5BLMNA | |
| SCHEMBL176349 | 0.97 | CA1 (0.52) | CA1CA4CA5ACA5BLMNA | |
| Water SCHEMBL28838465 | 0.94 | CA1 (0.50) | CA1CA4CA5ACA5BLMNA | |
| Zinc Ion SCHEMBL15261876 | 0.94 | CA1 (0.50) | CA1CA4CA5ACA5BLMNA | |
| Potassium Ion SCHEMBL10690609 | 0.94 | CA4 (0.50) | CA1CA4CA5ACA5BLMNA | |
| Potassium Ion SCHEMBL10798560 | 0.94 | CA4 (0.50) | CA1CA4CA5ACA5BLMNA | |
| SCHEMBL11523560 | 0.94 | — | — | |
| Silver SCHEMBL11521326 | 0.94 | CA1 (0.50) | CA1CA4CA5ACA5BLMNA | |
| SCHEMBL22532432 | 0.94 | — | — | |
| Lithium Ion SCHEMBL10598335 | 0.82 | ALDH1A1 (0.42) | CA1CA4CA5ACA5BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3406729-B1 | METHOD FOR ENZYMATIC PREPARATION OF FLUDARABINE PHOSPHATE | ZHEJIANG HISUN PHARM CO LTD (CN) | 2025-09-17 | — | — | EP | claimed |
| CN-117567555-A | Method for preparing glutathione by using enzyme method | 浙江普洛生物科技有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-117239242-A | Application of Lewis acid in preparation of lithium/fluorocarbon battery electrolyte | 厦门大学 | 2023-12-15 | — | — | CN | claimed |
| CN-114204106-B | Electrolyte additive for lithium ion battery, electrolyte and lithium ion battery | 松山湖材料实验室 | 2023-10-20 | — | — | CN | claimed |
| US-11421255-B2 | Method for enzymatic preparation of fludarabine phosphate | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2022-08-23 | — | — | US | claimed |
| CN-113224386-B | Cobalt acid lithium battery electrolyte additive, electrolyte and battery thereof | 松山湖材料实验室 | 2022-07-22 | — | — | CN | claimed |
| CN-113161610-B | Non-aqueous electrolyte for lithium ion battery and lithium ion battery comprising same | 松山湖材料实验室 | 2022-07-22 | — | — | CN | claimed |
| CN-113161611-B | Non-aqueous electrolyte for lithium ion battery and lithium ion battery comprising same | 松山湖材料实验室 | 2022-07-22 | — | — | CN | claimed |
| CN-114552006-A | Electrolyte additive composition and application | 香河昆仑新能源材料股份有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-113224386-A | Cobalt acid lithium battery electrolyte additive, electrolyte and battery thereof | 松山湖材料实验室 | 2021-08-06 | — | — | CN | claimed |
| CN-113161611-A | Non-aqueous electrolyte for lithium ion battery and lithium ion battery comprising same | 松山湖材料实验室 | 2021-07-23 | — | — | CN | claimed |
| CN-113161610-A | Non-aqueous electrolyte for lithium ion battery and lithium ion battery comprising same | 松山湖材料实验室 | 2021-07-23 | — | — | CN | claimed |
| US-20210198707-A1 | METHOD FOR ENZYMATIC PREPARATION OF FLUDARABINE PHOSPHATE | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2021-07-01 | — | — | US | claimed |
| CN-106755172-B | New way for synthesizing acetyl coenzyme A and derivative products thereof by using glycolaldehyde | 中国科学院天津工业生物技术研究所 | 2020-07-28 | — | — | CN | claimed |
| CN-109072272-A | Method for preparing fludarabine phosphate by enzyme method | 浙江海正药业股份有限公司 | 2018-12-21 | — | — | CN | claimed |
| EP-3406729-A1 | METHOD FOR ENZYMATIC PREPARATION OF FLUDARABINE PHOSPHATE | Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) | 2018-11-28 | — | — | EP | claimed |
| CN-104611396-A | Glutathione production method | SHANGHAI INST BIOL SCIENCES | 2015-05-13 | — | — | CN | claimed |
| EP-0153571-B1 | PROCESS FOR PREPARING SOLID ACETYL PHOSPHATE SALT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-19 | — | — | EP | claimed |
| US-4753757-A | FROM LITHIUM PHOSPHATE AND ACETIC ANHYDRIDE, PRECIPITATION | DAICEL CHEMICAL INDUSTRIES, INC. (JP) | 1988-06-28 | — | — | US | claimed |
| EP-3406729-B1 | METHOD FOR ENZYMATIC PREPARATION OF FLUDARABINE PHOSPHATE | ZHEJIANG HISUN PHARM CO LTD (CN) | 2025-09-17 | — | — | EP | disclosed |
| CN-119932001-A | Phosphoketolase mutant and application thereof in production of 3-hydroxypropionic acid | 北京化工大学 | 2025-05-06 | — | — | CN | disclosed |
| WO-2025081095-A1 | ENGINEERED ACETATE KINASE VARIANTS | CODEXIS, INC. (US) | 2025-04-17 | — | — | WO | disclosed |
| US-20250122487-A1 | ENGINEERED ACETATE KINASE VARIANTS | CODEXIS, INC. | 2025-04-17 | — | — | US | disclosed |
| CN-119685287-A | Acid-resistant enhanced nicotinamide riboside kinase mutant and application thereof | 南京诺云生物科技有限公司 | 2025-03-25 | — | — | CN | disclosed |
| US-20240218009-A1 | NOVEL FORMS OF CYCLIC DINUCLEOTIDE COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2024-07-04 | — | — | US | disclosed |
| US-20240199680-A1 | SYNTHESIS OF FLUORINATED CYCLIC DINUCLEOTIDES | MERCK SHARP & DOHME LLC (US) | 2024-06-20 | — | — | US | disclosed |
| US-20240182511-A1 | NOVEL FORMS OF CYCLIC DINUCLEOTIDE COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2024-06-06 | — | — | US | disclosed |
| WO-2024082328-A1 | BIOLOGICAL CATALYSIS METHOD FOR PREPARING ACETYL PHOSPHORIC ACID | 湖南祥民制药有限公司 | 2024-04-25 | — | — | WO | disclosed |
| CN-117567555-A | Method for preparing glutathione by using enzyme method | 浙江普洛生物科技有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-117239242-A | Application of Lewis acid in preparation of lithium/fluorocarbon battery electrolyte | 厦门大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-114204106-B | Electrolyte additive for lithium ion battery, electrolyte and lithium ion battery | 松山湖材料实验室 | 2023-10-20 | — | — | CN | disclosed |
| CN-116218813-A | Application of nicotinamide riboside kinase mutant | 南京诺云生物科技有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116162231-A | Normal pressure cationic dye dyeable polyester and production method and application thereof | 东丽纤维研究所（中国）有限公司 | 2023-05-26 | — | — | CN | disclosed |
| US-11634701-B2 | Metabolic pathways with increased carbon yield | TOTAL RAFFINAGE CHIMIE (FR) | 2023-04-25 | — | — | US | disclosed |
| CN-115873826-A | Nicotinamide ribokinase mutant | 南京诺云生物科技有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115595334-A | Biocatalysis method for preparing acetyl phosphate | 湖南祥民制药有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-110387379-B | Mixed culture process and application of recombinant escherichia coli for producing glutathione | 大连医诺生物股份有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-110373370-B | Catalytic system coupled with ATP regeneration system and application of catalytic system in glutathione production process | 大连医诺生物股份有限公司 | 2022-11-18 | — | — | CN | disclosed |
| WO-2022225827-A1 | NOVEL FORMS OF CYCLIC DINUCLEOTIDE COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2022-10-27 | — | — | WO | disclosed |
| WO-2022216577-A1 | NOVEL FORMS OF CYCLIC DINUCLEOTIDE COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2022-10-13 | — | — | WO | disclosed |
| US-11421255-B2 | Method for enzymatic preparation of fludarabine phosphate | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2022-08-23 | — | — | US | disclosed |
| CN-113224386-B | Cobalt acid lithium battery electrolyte additive, electrolyte and battery thereof | 松山湖材料实验室 | 2022-07-22 | — | — | CN | disclosed |
| CN-113161610-B | Non-aqueous electrolyte for lithium ion battery and lithium ion battery comprising same | 松山湖材料实验室 | 2022-07-22 | — | — | CN | disclosed |
| CN-113161612-B | Non-aqueous electrolyte for lithium ion battery and lithium ion battery comprising same | 松山湖材料实验室 | 2022-07-22 | — | — | CN | disclosed |
| CN-113161611-B | Non-aqueous electrolyte for lithium ion battery and lithium ion battery comprising same | 松山湖材料实验室 | 2022-07-22 | — | — | CN | disclosed |
| CN-114552006-A | Electrolyte additive composition and application | 香河昆仑新能源材料股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114369633-A | Preparation method of 6-allose phosphate, acetyl phosphate and acetyl coenzyme A | 中国科学院天津工业生物技术研究所 | 2022-04-19 | — | — | CN | disclosed |
| CN-114204106-A | Lithium ion battery electrolyte additive, electrolyte and lithium ion battery | 松山湖材料实验室 | 2022-03-18 | — | — | CN | disclosed |
| CN-112086684-B | Cesium-containing high-voltage lithium ion battery electrolyte composite additive, electrolyte and battery thereof | 松山湖材料实验室 | 2022-01-11 | — | — | CN | disclosed |
| CN-113584104-A | Method for synthesizing fludarabine phosphate through biocatalysis | 江苏海洋大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-113224386-A | Cobalt acid lithium battery electrolyte additive, electrolyte and battery thereof | 松山湖材料实验室 | 2021-08-06 | — | — | CN | disclosed |
| CN-113161611-A | Non-aqueous electrolyte for lithium ion battery and lithium ion battery comprising same | 松山湖材料实验室 | 2021-07-23 | — | — | CN | disclosed |
| CN-113161610-A | Non-aqueous electrolyte for lithium ion battery and lithium ion battery comprising same | 松山湖材料实验室 | 2021-07-23 | — | — | CN | disclosed |
| CN-113161612-A | Non-aqueous electrolyte for lithium ion battery and lithium ion battery comprising same | 松山湖材料实验室 | 2021-07-23 | — | — | CN | disclosed |
| US-20210198707-A1 | METHOD FOR ENZYMATIC PREPARATION OF FLUDARABINE PHOSPHATE | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2021-07-01 | — | — | US | disclosed |
| US-20210189372-A1 | Metabolic Pathways with Increased Carbon Yield | TOTALENERGIES ONETECH (FR) | 2021-06-24 | — | — | US | disclosed |
| CN-111254129-B | Polyphosphate kinase mutant and application thereof | 浙江华睿生物技术有限公司 | 2021-06-08 | — | — | CN | disclosed |
| CN-108753808-B | Recombinant expression vector, recombinant expression host and method for synthesizing adenosine triphosphate by using recombinant expression vector | 浙江海正药业股份有限公司 | 2021-02-23 | — | — | CN | disclosed |
| EP-3759224-A1 | METABOLIC PATHWAYS WITH INCREASED CARBON YIELD | Total Raffinage Chimie (FR) | 2021-01-06 | — | — | EP | disclosed |
| CN-112086684-A | Cesium-containing high-voltage lithium ion battery electrolyte composite additive, electrolyte and battery thereof | 松山湖材料实验室 | 2020-12-15 | — | — | CN | disclosed |
| CN-110133091-B | Application of 05SAR-PAGE | 中国科学院武汉物理与数学研究所 | 2020-08-28 | — | — | CN | disclosed |
| CN-106755172-B | New way for synthesizing acetyl coenzyme A and derivative products thereof by using glycolaldehyde | 中国科学院天津工业生物技术研究所 | 2020-07-28 | — | — | CN | disclosed |
| CN-111254129-A | Polyphosphate kinase mutant and application thereof | 浙江华睿生物技术有限公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-110387379-A | It is a kind of for producing the mixed culture technique and its application of the recombination bacillus coli of glutathione | 大连医诺生物股份有限公司 | 2019-10-29 | — | — | CN | disclosed |
| CN-110373370-A | A kind of catalyst system of coupling ATP regenerative system and its application during producing glutathione | 大连医诺生物股份有限公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-110133091-A | 05SAR-PAGE and its preparation method and application | 中国科学院武汉物理与数学研究所 | 2019-08-16 | — | — | CN | disclosed |
| CN-109072272-A | Method for preparing fludarabine phosphate by enzyme method | 浙江海正药业股份有限公司 | 2018-12-21 | — | — | CN | disclosed |
| EP-3406729-A1 | METHOD FOR ENZYMATIC PREPARATION OF FLUDARABINE PHOSPHATE | Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) | 2018-11-28 | — | — | EP | disclosed |
| CN-108753808-A | A kind of recombinant expression carrier, recombinant expression host and its method for synthesizing adenosine triphosphoric acid | 浙江海正药业股份有限公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-104611396-B | A method of producing glutathione | 中国科学院上海生命科学研究院 | 2018-09-04 | — | — | CN | disclosed |
| CN-104630300-B | A kind of l-amino acid production method | 中国科学院上海生命科学研究院 | 2018-06-22 | — | — | CN | disclosed |
| CN-105906662-B | Method for continuously producing acetyl phosphate by using microchannel reaction device | 南京工业大学 | 2018-02-13 | — | — | CN | disclosed |
| CN-107474231-A | A kind of atmospheric cation dyeable polyester and its production method and purposes | 东丽纤维研究所（中国）有限公司 | 2017-12-15 | — | — | CN | disclosed |
| CN-104263772-B | A kind of method that acetyl phosphate is prepared based on biology enzyme | 湖南福来格生物技术有限公司 | 2017-07-28 | — | — | CN | disclosed |
| CN-105906662-A | Method for continuously producing acetyl phosphate by using microchannel reaction device | 南京工业大学 | 2016-08-31 | — | — | CN | disclosed |
| CN-104860984-A | Preparation method of acetyl diammonium phosphate | ZHEJIANG HISUN PHARM CO LTD | 2015-08-26 | — | — | CN | disclosed |
| CN-104630300-A | Production method of L-amino acid | SHANGHAI INST BIOL SCIENCES | 2015-05-20 | — | — | CN | disclosed |
| CN-104611396-A | Glutathione production method | SHANGHAI INST BIOL SCIENCES | 2015-05-13 | — | — | CN | disclosed |
| CN-104263772-A | Method for preparing acetyl phosphate on basis of biological enzymes | HUNAN FLAG BIO TECH CO LTD | 2015-01-07 | — | — | CN | disclosed |
| CN-104130283-A | Preparation method of high energy phosphoric acid compound | HUNAN FLAG BIO TECH CO LTD | 2014-11-05 | — | — | CN | disclosed |
| US-20040242471-A1 | Dormancy induced mycobacterium proteins | INSTITUTE OF MOLECULAR AND CELL BIOLOGY (SG) | 2004-12-02 | — | — | US | disclosed |
| US-6824994-B2 | USING PEPTIDE MIMETICS TO PREVENT BINDING AND GENE EXPRESSION ACTIVATION BY PHOSPHORYLATED ASPARTYL REGULATORY PROTEIN; DECREASING DEVELOPMENT OF ANTIBIOTIC RESISTANCE IN PATHOGENIC BACTERIA; GENE EXPRESSION INHIBITION | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2004-11-30 | — | — | US | disclosed |
| US-20040033534-A1 | Peptide ligands that mimic sensor kinases and inhibit reseponse regulators | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-02-19 | — | — | US | disclosed |
| CN-1117870-C | Method for producing nucleoside-5' -phosphate ester | AJINOMOTO KK (JP) | 2003-08-13 | — | — | CN | disclosed |
| WO-2002048391-A2 | DORMANCY - INDUCED MYCOBACTERIUM PROTEINS | INSTITUTE OF MOLECULAR AND CELL BIOLOGY (SG) | 2002-06-20 | — | — | WO | disclosed |
| WO-2001049708-A2 | PEPTIDE LIGANDS THAT MIMIC SENSOR KINASES AND INHIBIT RESPONSE REGULATORS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2001-07-12 | — | — | WO | disclosed |
| CN-1184157-A | Method for producing nucleoside-5' -phosphate ester | AJINOMOTO KK (JP) | 1998-06-10 | — | — | CN | disclosed |
| EP-0153571-B1 | PROCESS FOR PREPARING SOLID ACETYL PHOSPHATE SALT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-19 | — | — | EP | disclosed |
| US-4753757-A | FROM LITHIUM PHOSPHATE AND ACETIC ANHYDRIDE, PRECIPITATION | DAICEL CHEMICAL INDUSTRIES, INC. (JP) | 1988-06-28 | — | — | US | disclosed |
| EP-0153571-A1 | Process for preparing solid acetyl phosphate salt | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1985-09-04 | — | — | EP | disclosed |
| US-4164444-A | Method for preparing adenosine triphosphate | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1979-08-14 | — | — | US | disclosed |
| US-4088675-A | Production of acyl phosphate salts | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4088675-A | Production of acyl phosphate salts | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1978-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240218009-A1 | NOVEL FORMS OF CYCLIC DINUCLEOTIDE COMPOUNDS | STING1, IFNAR1, CGAS | CA1 4769/4885CA4 4843/4885CA5A 1503/4885 |
| US-20240199680-A1 | SYNTHESIS OF FLUORINATED CYCLIC DINUCLEOTIDES | NT5C3B, DUT, NT5C2 | CA1 4402/4885CA4 4569/4885CA5A 727/4885 |
| US-20240182511-A1 | NOVEL FORMS OF CYCLIC DINUCLEOTIDE COMPOUNDS | STING1, IFNAR1, CGAS | CA1 4627/4885CA4 4676/4885CA5A 1054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.