Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.53 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | PRKCG | P05129 | 1/20 | 0.53 |
| ▸ | PRKCB | P05771 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511787 | 0.92 | KDM4E (0.51) | KDM4EALOX15HSD17B10MAPTALDH1A1 | |
| SCHEMBL6085735 | 0.90 | HTT (0.52) | KDM4EALOX15HSD17B10MAPTALDH1A1 | |
| SCHEMBL1202543 | 0.84 | IMPDH2 (0.63) | KDM4EALOX15HSD17B10MAPTALDH1A1 | |
| SCHEMBL28377762 | 0.77 | NR4A2 (0.81) | HSD17B10MAPTALDH1A1IMPDH2SIRT2 | |
| 3-Phenylindole SCHEMBL29609072 | 0.76 | IMPDH2 (0.71) | HSD17B10MAPTALDH1A1IMPDH2SIRT2 | |
| 3-Phenylindole SCHEMBL84056 | 0.76 | IMPDH2 (0.71) | HSD17B10MAPTALDH1A1IMPDH2SIRT2 | |
| SCHEMBL28416622 | 0.76 | NR4A2 (0.78) | HSD17B10MAPTALDH1A1IMPDH2SIRT2 | |
| SCHEMBL14188727 | 0.76 | HSD17B10 (0.55) | KDM4EALOX15HSD17B10MAPTALDH1A1 | |
| SCHEMBL29942046 | 0.76 | HSD17B10 (0.55) | KDM4EALOX15HSD17B10MAPTALDH1A1 | |
| SCHEMBL28129193 | 0.75 | HSD17B10 (0.51) | KDM4EALOX15HSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | claimed |
| EP-1370519-A1 | SYNTHETIC EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2003-12-17 | — | — | EP | claimed |
| WO-2002068380-A1 | SYNTHETIC EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2002-09-06 | — | — | WO | claimed |
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |
| EP-1370519-A1 | SYNTHETIC EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002068380-A1 | SYNTHETIC EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |