3-Phenylindole

3-Phenylindole

SCHEMBL84056

c1ccc(-c2c[nH]c3ccccc23)cc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 3/20 0.71
NR4A2 P43354 1/20 0.71
MAPK1 P28482 1/20 0.71
HSD17B10 Q99714 1/20 0.71
PARP1 P09874 1/20 0.61
MAPT P10636 3/20 0.58
NPSR1 Q6W5P4 2/20 0.58
ALDH1A1 P00352 1/20 0.58
LMNA P02545 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2D6 P10635 1/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2C19 P33261 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
GPR55 Q9Y2T6 1/20 0.58
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
ASH1L Q9NR48 1/20 0.57
TDP1 Q9NUW8 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Phenylindole SCHEMBL29609072 1.00 IMPDH2 (0.71) IMPDH2NR4A2MAPK1HSD17B10PARP1
SCHEMBL28377762 0.93 NR4A2 (0.81) IMPDH2NR4A2MAPK1HSD17B10MAPT
SCHEMBL28416622 0.91 NR4A2 (0.78) IMPDH2NR4A2MAPK1HSD17B10MAPT
SCHEMBL1202543 0.85 IMPDH2 (0.63) IMPDH2NR4A2MAPK1HSD17B10MAPT
SCHEMBL1923969 0.84 PARP1 (0.58) IMPDH2NR4A2MAPK1HSD17B10PARP1
SCHEMBL1781166 0.84 IMPDH2 (0.62) IMPDH2NR4A2MAPK1HSD17B10MAPT
SCHEMBL11515884 0.84 ALOX5 (0.71) IMPDH2NR4A2MAPK1HSD17B10MAPT
SCHEMBL1071072 0.84 NR4A2 (0.68) IMPDH2NR4A2MAPK1HSD17B10ASH1L
SCHEMBL31517691 0.84 NR4A2 (0.68) IMPDH2NR4A2MAPK1HSD17B10MAPT
SCHEMBL1879218 0.84 NR4A2 (1.00) IMPDH2NR4A2MAPK1HSD17B10ASH1L

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 445 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114014859-A Triazole indolol compound and synthesis method thereof 绍兴文理学院 2022-02-08 CN claimed
CN-113616641-A Application of 3-phenylindole derivative in preparation of antifungal drugs 云南中医药大学 2021-11-09 CN claimed
CN-113200904-A Indole compound and preparation method and application thereof 广东工业大学 2021-08-03 CN claimed
CN-110467555-B Axial chiral aryl indole compound and synthesis method thereof 江苏师范大学 2020-11-24 CN claimed
CN-107056678-A Organic nonlinear optical crystal material PBSB and preparation process thereof 青岛大学 2017-08-18 CN claimed
CN-105037422-B Preparation method of indole phosphonate derivative 苏州大学 2017-05-10 CN claimed
EP-2844500-B1 PNEUMATIC OBJECT PROVIDED WITH A GASTIGHT LAYER BASED ON A THERMOPLASTIC ELASTOMER AND ON A LAMELLAR FILLER MICHELIN & CIE (FR) 2016-03-23 EP claimed
CN-105037422-A Preparation method of indole phosphonate derivative UNIV SOOCHOW 2015-11-11 CN claimed
CN-104926868-A Method for preparing indole phosphonate derivative ZHANGJIAGANG INST IND TECHNOLOGIES SOOCHOW UNIV 2015-09-23 CN claimed
US-6670053-B2 Employing interlayer comprising compound containing 3-phenylindolyl group between hole transport layer and light emitting layer EASTMAN KODAK COMPANY 2003-12-30 US claimed
US-20030180573-A1 Organic electroluminescent devices with high luminance EASTMAN KODAK COMPANY 2003-09-25 US claimed
CN-1441628-A Organic electroluminescence device with high brightness EASTMAN KODAK CO (US) 2003-09-10 CN claimed
EP-1339264-A2 Organic electroluminescent devices with high luminance EASTMAN KODAK COMPANY (US) 2003-08-27 EP claimed
US-5936098-A Process for producing indoline compounds and intermediates for the production of the same TOKYO TANABE COMPANY LIMITED (JP) 1999-08-10 US claimed
EP-0810214-A1 PROCESS FOR PRODUCING INDOLINE COMPOUNDS AND INTERMEDIATES FOR THE PRODUCTION OF THE SAME TOKYO TANABE COMPANY LIMITED (JP) 1997-12-03 EP claimed
EP-0000972-A2 2-Substituted-3-phenylindoles, their preparation, and pharmaceutical compositions containing them Technobiotic Ltd. (CH) 1979-03-07 EP claimed
US-3989714-A ANTIVIRAL WARNER-LAMBERT COMPANY (US) 1976-11-02 US claimed
JP-53071066-A None JP disclosed
US-3989714-A ANTIVIRAL WARNER-LAMBERT COMPANY (US) 1976-11-02 US disclosed
US-3957513-A Method of free radical photography utilizing a short light flash for exposure ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-05-18 US disclosed