Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.71 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Phenylindole SCHEMBL84056 | 1.00 | IMPDH2 (0.71) | IMPDH2NR4A2MAPK1HSD17B10PARP1 | |
| SCHEMBL28377762 | 0.93 | NR4A2 (0.81) | IMPDH2NR4A2MAPK1HSD17B10MAPT | |
| SCHEMBL28416622 | 0.91 | NR4A2 (0.78) | IMPDH2NR4A2MAPK1HSD17B10MAPT | |
| SCHEMBL1202543 | 0.85 | IMPDH2 (0.63) | IMPDH2NR4A2MAPK1HSD17B10MAPT | |
| SCHEMBL1923969 | 0.84 | PARP1 (0.58) | IMPDH2NR4A2MAPK1HSD17B10PARP1 | |
| SCHEMBL1781166 | 0.84 | IMPDH2 (0.62) | IMPDH2NR4A2MAPK1HSD17B10MAPT | |
| SCHEMBL11515884 | 0.84 | ALOX5 (0.71) | IMPDH2NR4A2MAPK1HSD17B10MAPT | |
| SCHEMBL1071072 | 0.84 | NR4A2 (0.68) | IMPDH2NR4A2MAPK1HSD17B10ASH1L | |
| SCHEMBL31517691 | 0.84 | NR4A2 (0.68) | IMPDH2NR4A2MAPK1HSD17B10MAPT | |
| SCHEMBL1879218 | 0.84 | NR4A2 (1.00) | IMPDH2NR4A2MAPK1HSD17B10ASH1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050433-A1 | ALLOSTERIC MODULATORS OF ANDROGEN RECEPTOR COACTIVATOR RECRUITMENT FOR CRPC THERAPY | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2024-03-07 | — | — | WO | disclosed |
| EP-4251633-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2023-10-04 | — | — | EP | disclosed |
| WO-2022109741-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2022-06-02 | — | — | WO | disclosed |