Phosphoric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRB1 ADRB2 ADRB3 CYP11B1 DPP4 FGFR1 FGFR2 FGFR3 FGFR4 HRH1 JAK1 JAK2 JAK3 KCNA1 KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 KDR KIT NA OPRD1 OPRK1 OPRM1 P PDGFRB PIK3CD SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SMO TYK2 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY2	P41231	12/20	0.44

▸	P2RY4	P51582	5/20	0.44

▸	KDM4E	B2RXH2	1/20	0.39

▸	APAF1	O14727	1/20	0.39

▸	NSD2	O96028	1/20	0.39

▸	ALDH1A1	P00352	1/20	0.39

▸	HPGD	P15428	1/20	0.39

▸	CASP3	P42574	1/20	0.39

▸	SENP8	Q96LD8	1/20	0.39

▸	HSD17B10	Q99714	1/20	0.39

▸	SENP7	Q9BQF6	1/20	0.39

▸	SENP6	Q9GZR1	1/20	0.39

▸	TSHR	P16473	1/20	0.36

▸	LMNA	P02545	1/20	0.36

▸	MAPT	P10636	1/20	0.36

▸	PMP22	Q01453	1/20	0.36

▸	HBB	P68871	1/20	0.36

▸	SMN1; SMN2	Q16637	1/20	0.36

▸	ADK	P55263	3/20	0.34

▸	P2RY14	Q15391	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Phosphoric Acid SCHEMBL6798894	0.86	P2RY2 (0.57)	P2RY2P2RY4KDM4EAPAF1NSD2
Phosphoric Acid SCHEMBL6797772	0.85	P2RY2 (0.46)	P2RY2P2RY4TSHRLMNAMAPT
Phosphoric Acid SCHEMBL6796820	0.84	P2RY2 (0.47)	P2RY2P2RY4TSHRLMNAMAPT
SCHEMBL6795888	0.78	P2RY2 (0.64)	P2RY2P2RY4P2RY6
SCHEMBL6804528	0.76	LMNA (0.50)	P2RY2P2RY4LMNAMAPTADK
SCHEMBL22796988	0.76	LMNA (0.50)	P2RY2P2RY4LMNAMAPTADK
SCHEMBL6804524	0.76	LMNA (0.50)	P2RY2P2RY4LMNAMAPTADK
SCHEMBL6007584	0.74	ADK (0.40)	KDM4EAPAF1NSD2ALDH1A1HPGD
Phosphoric Acid SCHEMBL6798829	0.74	P2RY2 (0.61)	P2RY2P2RY4
Phosphoric Acid SCHEMBL6798587	0.74	P2RY2 (0.61)	P2RY2P2RY4TSHRLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20040122223-A1	Non-natural nucleotides and dinucleotides	CELLTECH R & D LIMITED (GB)	2004-06-24	—	—	US	claimed
US-20040122223-A1	Non-natural nucleotides and dinucleotides	CELLTECH R & D LIMITED (GB)	2004-06-24	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20040122223-A1	Non-natural nucleotides and dinucleotides	P2RY1, P2RY11, P2RY13	P2RY2 8/4885P2RY4 6/4885KDM4E 4880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.