Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL952227 | 0.77 | CYP2C19 (0.38) | CYP2C19LMNACYP2D6SRCALDH1A1 | |
| SCHEMBL296773 | 0.77 | TSHR (0.39) | CYP2C19LMNAALDH1A1KDM4ECYP3A4 | |
| SCHEMBL2347870 | 0.77 | DPP4 (0.39) | CYP2C19LMNAALDH1A1KDM4ECYP3A4 | |
| SCHEMBL28971499 | 0.76 | KDM4E (0.37) | CYP2C19LMNAALDH1A1KDM4ECYP3A4 | |
| SCHEMBL876939 | 0.72 | CYP2C19 (0.35) | CYP2C19LMNAALDH1A1KDM4ECYP3A4 | |
| SCHEMBL28478936 | 0.72 | LMNA (0.39) | LMNAALDH1A1KDM4ECYP3A4 | |
| SCHEMBL5135542 | 0.71 | SCN4A (0.32) | CYP2C19LMNAALDH1A1KDM4ECYP3A4 | |
| SCHEMBL28693790 | 0.70 | KDM4E (0.33) | CYP2C19LMNACYP2D6ALDH1A1KDM4E | |
| SCHEMBL96576 | 0.69 | TSHR (0.43) | CYP2C19LMNACYP2D6SRCALDH1A1 | |
| SCHEMBL3893413 | 0.69 | TSHR (0.43) | CYP2C19LMNACYP2D6SRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7347970-B2 | Biocides based on silanol terminated silanes and siloxanes | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-03-25 | — | — | US | claimed |
| CN-1314086-C | Process for wafer level treatment to reduce stiction and passivate micromachined surfaces and compound used therefor | ANALAG DEVICES INC (US) | 2007-05-02 | — | — | CN | claimed |
| US-20060194764-A1 | Biocides based on silanol terminated silanes and siloxanes | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2006-08-31 | — | — | US | claimed |
| WO-2006028491-A1 | BIOCIDES BASED ON SILANOL TERMINATED SILANES AND SILOXANES | UNIVERSITY OF FLORIDA (US) | 2006-03-16 | — | — | WO | claimed |
| WO-2017036618-A1 | SILICONE RUBBER COMPOSITION FOR AIRBAG SEALING MATERIAL | WACKER CHEMIE AG (DE) | 2017-03-09 | — | — | WO | disclosed |
| US-9512272-B2 | Curable composition containing silicone, and cured product thereof | CENTRAL GLASS COMPANY, LIMITED (JP) | 2016-12-06 | — | — | US | disclosed |
| US-20150322211-A1 | Curable Composition Containing Silicone, and Cured Product Thereof | CENTRAL GLASS COMPANY, LIMITED (JP) | 2015-11-12 | — | — | US | disclosed |
| US-8679518-B2 | Antimicrobial compounds having protective or therapeutic leaving groups | MEDTRONIC, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20120157373-A1 | ANTIMICROBIAL COMPOUNDS HAVING PROTECTIVE OR THERAPEUTIC LEAVING GROUPS | MEDTRONIC, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-8173622-B2 | Antimicrobial compounds having protective or therapeutic leaving groups | MEDTRONIC, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| WO-2011149894-A2 | ANTIMICROBIAL COMPOSITIONS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2011-12-01 | — | — | WO | disclosed |
| US-20110287074-A1 | Antimicrobial Compositions, Methods of Manufacture Thereof and Articles Comprising the Same | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2011-11-24 | — | — | US | disclosed |
| US-7347970-B2 | Biocides based on silanol terminated silanes and siloxanes | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-03-25 | — | — | US | disclosed |
| US-20060194764-A1 | Biocides based on silanol terminated silanes and siloxanes | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2006-08-31 | — | — | US | disclosed |
| US-20060194764-A1 | Biocides based on silanol terminated silanes and siloxanes | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2006-08-31 | — | — | US | disclosed |
| WO-2006028491-A1 | BIOCIDES BASED ON SILANOL TERMINATED SILANES AND SILOXANES | UNIVERSITY OF FLORIDA (US) | 2006-03-16 | — | — | WO | disclosed |
| WO-2006028491-A1 | BIOCIDES BASED ON SILANOL TERMINATED SILANES AND SILOXANES | UNIVERSITY OF FLORIDA (US) | 2006-03-16 | — | — | WO | disclosed |
| CN-87105866-A | PESTICIDAL COMPOSITION | — | 1988-05-04 | — | — | CN | disclosed |
| EP-0258055-A2 | A new pesticidal composition | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1988-03-02 | — | — | EP | disclosed |
| EP-0237271-A2 | A sesquilignan derivative | Nippon Kayaku Kabushiki Kaisha (JP) | 1987-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287074-A1 | Antimicrobial Compositions, Methods of Manufacture Thereof and Articles Comprising the Same | MSR1, TAS1R3, TAS2R3 | CYP2C19 3962/4885LMNA 3215/4885CYP2D6 3993/4885 |
| US-20120157373-A1 | ANTIMICROBIAL COMPOUNDS HAVING PROTECTIVE OR THERAPEUTIC LEAVING GROUPS | LTN1, VIP, CTSA | CYP2C19 3176/4885LMNA 1167/4885CYP2D6 3745/4885 |
| US-20060194764-A1 | Biocides based on silanol terminated silanes and siloxanes | MSR1, S1PR3, TAS2R3 | CYP2C19 3602/4885LMNA 3550/4885CYP2D6 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.