Sugi Predict

Sugi Predict / Compounds / SCHEMBL296773

SCHEMBL296773

SCHEMBL296773

C=CC([SiH2]Cl)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.39
▸ CYP2C19 P33261 1/20 0.38
▸ CYP3A4 P08684 4/20 0.34
▸ KDM4E B2RXH2 4/20 0.34
▸ MAPT P10636 4/20 0.34
▸ ALOX15 P16050 3/20 0.34
▸ ALDH1A1 P00352 3/20 0.33
▸ DPP4 P27487 2/20 0.33
▸ F2 P00734 1/20 0.33
▸ HTR2A P28223 2/20 0.32
▸ HRH1 P35367 1/20 0.32
▸ LMNA P02545 2/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ TDP1 Q9NUW8 3/20 0.31
▸ TAAR1 Q96RJ0 1/20 0.31
▸ HPGD P15428 3/20 0.30
▸ USP2 O75604 2/20 0.30
▸ TP53 P04637 2/20 0.30
▸ HSD17B10 Q99714 2/20 0.30
▸ ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL952227 0.77 CYP2C19 (0.38) TSHRCYP2C19CYP3A4KDM4EMAPT
SCHEMBL2347870 0.77 DPP4 (0.39) TSHRCYP2C19CYP3A4KDM4EMAPT
SCHEMBL679594 0.77 CYP2C19 (0.38) TSHRCYP2C19CYP3A4KDM4EMAPT
SCHEMBL876939 0.77 CYP2C19 (0.35) TSHRCYP2C19CYP3A4KDM4EMAPT
SCHEMBL28971499 0.76 KDM4E (0.37) TSHRCYP2C19CYP3A4KDM4EMAPT
SCHEMBL28478936 0.72 LMNA (0.39) CYP3A4KDM4EALDH1A1HTR2AHRH1
SCHEMBL5135542 0.71 SCN4A (0.32) TSHRCYP2C19CYP3A4KDM4EMAPT
SCHEMBL28693790 0.70 KDM4E (0.33) CYP2C19CYP3A4KDM4EMAPTALOX15
SCHEMBL296868 0.69 LMNA (0.34) CYP2C19CYP3A4KDM4EMAPTALOX15
SCHEMBL109223 0.69 TSHR (0.50) TSHRCYP2C19CYP3A4KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2276793-B1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INT (FR) 2012-08-01 — — EP claimed
EP-2470574-A2 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION Bridgestone Corporation (JP) 2012-07-04 — — EP claimed
US-20120165484-A1 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORPORATION (JP) 2012-06-28 — — US claimed
EP-2287231-B1 Ulltraviolet transmissive polyhedral silsesquioxane polymers PANASONIC CORP (JP) 2012-06-06 — — EP claimed
US-8063237-B2 Sulfur modified silanes for the elaboration of high refractive index materials ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2011-11-22 — — US claimed
US-20110251357-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS PANASONIC ELECTRIC WORKS CO., LTD. 2011-10-13 — — US claimed
US-20110077341-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INTERNATIONAL (FR) 2011-03-31 — — US claimed
WO-2011028523-A2 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORPORATION (JP) 2011-03-10 — — WO claimed
EP-2287231-A2 Ulltraviolet transmissive polyhedral silesquioxane polymers Panasonic Electric Works Co., Ltd. (JP) 2011-02-23 — — EP claimed
EP-2276793-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS Essilor International (Compagnie Générale d'Optique) (FR) 2011-01-26 — — EP claimed
WO-2009138853-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INTERNATIONAL (FR) 2009-11-19 — — WO claimed
JP-2008523165-A — — 2008-07-03 — — JP claimed
EP-1833880-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS Matsushita Electric Works, Ltd. (JP) 2007-09-19 — — EP claimed
WO-2006062219-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2006-06-15 — — WO claimed
US-20060122351-A1 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2006-06-08 — — US claimed
US-20250326936-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2025-10-23 — — US disclosed
US-12173166-B2 Articles including surface coatings and methods to produce them MAXTERIAL, INC. (US) 2024-12-24 — — US disclosed
US-20050287392-A1 Organic electroluminescent device, method for producing the same, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2005-12-29 — — US disclosed
US-6777570-B2 Process for producing norbornene derivative having organosilyl group MITSUBISHI CHEMICAL CORPORATION (JP) 2004-08-17 — — US disclosed
US-20040063982-A1 Process for producing norbornene derivative having organosilyl group MITSUBISHI CHEMICAL CORPORATION (JP) 2004-04-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110077341-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS TST, LAGE3, PSME1 TSHR 3396/4885CYP2C19 2671/4885CYP3A4 2359/4885
US-20040063982-A1 Process for producing norbornene derivative having organosilyl group GRIA2, GRM2, GRM8 TSHR 1793/4885CYP2C19 2223/4885CYP3A4 685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.