SCHEMBL6796911

SCHEMBL6796911

Cc1ccc(COc2[c]cccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.44
AGXT P21549 2/20 0.42
KCNH2 Q12809 1/20 0.41
NPC1 O15118 4/20 0.40
HTR1A P08908 1/20 0.40
ADRA1D P25100 1/20 0.40
ADRA1A P35348 1/20 0.40
ADRA1B P35368 1/20 0.40
HTT P42858 1/20 0.40
MAOA P21397 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
ALDH1A1 P00352 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 1/20 0.38
PARP10 Q53GL7 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CARM1 Q86X55 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5790467 0.86 TP53 (0.40) NPC1SMN1; SMN2ALDH1A1KMT2ALMNA
SCHEMBL95381 0.85 TSHR (0.44) MAOBAGXTHTR1AMAOASMN1; SMN2
SCHEMBL10830875 0.84 TACR1 (0.41) MAOBPARP10
SCHEMBL7086574 0.84 LMNA (0.48) SMN1; SMN2ALDH1A1KMT2ALMNAMAPT
SCHEMBL10840200 0.83 KCNH2 (0.43) MAOBKCNH2NPC1MAOATDP1
SCHEMBL2451926 0.83 APP (0.49) MAOBAGXTNPC1HTR1AADRA1D
SCHEMBL2451731 0.82 MAOB (0.43) MAOBAGXTNPC1HTR1AHTT
SCHEMBL3973667 0.82 IDO1 (0.48) AGXTHTTKMT2ALMNACARM1
SCHEMBL1907545 0.82 MAOB (0.43) MAOBAGXTNPC1HTR1AADRA1D
SCHEMBL28555541 0.81 MAOB (0.50) MAOBHTR1AADRA1DADRA1AADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0476648-B1 Polymeric ammonium borates and process for their preparation HOECHST AG (DE) 1995-06-21 EP claimed
EP-0476648-A1 Polymeric ammonium borates and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1992-03-25 EP claimed
EP-0476647-A1 Polymeric ammonium compounds as charge directors HOECHST AKTIENGESELLSCHAFT (DE) 1992-03-25 EP claimed
CN-108329330-B 2-benzyloxy phenyl oxazolopyridine compound and pharmaceutical application thereof 复旦大学 2021-05-04 CN disclosed
WO-2004094542-A1 INKJET PRINTING METHOD EASTMAN KODAK COMPANY (US) 2004-11-04 WO disclosed
US-4578107-A Herbicidal imidazolidine-2-one derivatives OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1986-03-25 US disclosed
US-4567268-A Process for preparation of certain tetrahydrofuro[3,4-b]pyridines MERCK & CO., INC. (US) 1986-01-28 US disclosed